Kuwabara T, Funahashi M
Invest Ophthalmol. 1976 May;15(5):407-11.
The photoreceptor synapses of albino rats show considerable pathologic changes following fluorescent light exposure. The changes in the synapses and in the lamellar membranes of the outer segments occur and progress simultaneously. Membranes proliferate in the paramitochondrial zone of the rod synaptic spherule and fine budding of the smooth endoplasmic reticulum occurs in the cone pedicle within one hour's exposure to the brightness of 500 foot candles. Proliferating paramitochondrial membranes have no cytochrome c oxidase activity and degenerate together with mitochondria by further exposure. The cone pedicles remain relatively intact in photically damaged retina.
白化大鼠的光感受器突触在荧光暴露后会出现相当程度的病理变化。突触和外段层状膜的变化同时发生并进展。在暴露于500英尺烛光亮度一小时内，杆状突触小球的线粒体外区膜会增殖，而锥体细胞突触小体中的光滑内质网会出现细微出芽。增殖的线粒体外膜没有细胞色素c氧化酶活性，进一步暴露后会与线粒体一起退化。在光损伤的视网膜中，锥体细胞突触小体相对保持完整。
