Young R H, Silva E G, Scully R E
Department of Pathology, Harvard Medical School, James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston.
Int J Gynecol Pathol. 1991;10(4):364-71. doi: 10.1097/00004347-199110000-00009.
Five ovarian adenomatoid tumors and one juxtaovarian tumor of this type in women 23 to 79 (average 54) years of age are described. Four were less than or equal to 7 mm in diameter; the other two were 1.4 cm and 5 cm. The five ovarian tumors were located predominantly in the hilus, with focal extension into the medulla. Microscopic examination showed the lesions to be characterized by round, oval, or elongated tubules, some of which were cystically dilated, and vacuoles occasionally containing basophilic secretion. Hyaline bodies were present in one case. Follow-up in these cases and the 10 previously reported similar cases that include follow-up information has been benign. The microscopic features of the ovarian adenomatoid tumor are typically diagnostic, but, as illustrated by one of our cases and another in the literature, some features that simulate those of yolk sac tumor may cause diagnostic difficulty when the tumor occurs in a young patient.
本文描述了5例卵巢腺瘤样瘤及1例发生于23至79岁(平均54岁)女性的此类卵巢旁肿瘤。4例直径小于或等于7mm;另外2例分别为1.4cm和5cm。5例卵巢肿瘤主要位于卵巢门,局部延伸至髓质。显微镜检查显示,病变的特征为圆形、椭圆形或细长形小管,部分呈囊性扩张,还有偶尔含有嗜碱性分泌物的空泡。1例出现透明小体。这些病例以及之前报道的10例包含随访信息的类似病例的随访结果均为良性。卵巢腺瘤样瘤的显微镜特征通常具有诊断性,但正如我们的1例病例及文献中的另一例所示,当肿瘤发生于年轻患者时,一些模拟卵黄囊瘤的特征可能会导致诊断困难。