Pomeranz S, Constantini S, Umansky F
Neurosurgery Department, Hadassah University Hospital, Jerusalem, Israel.
Neurochirurgia (Stuttg). 1991 Nov;34(6):166-9. doi: 10.1055/s-2008-1052082.
Cerebrospinal fluid leakage is one of the central problems facing neurosurgeons, both due to its occasional difficulty in management and to the catastrophical significance of ensuing infection. An important tool emerging in the surgical management of CSF leakage is fibrin sealant, the natural coagulation product. Thirteen cases of CSF leakage, due to meningomyelocele, posttraumatic, and secondary to tumor, that were managed surgically with fibrin sealant are presented. Several of the cases were successfully operated upon following failure of conventional surgical techniques. Additional uses of fibrin sealant in neurosurgery are discussed.
脑脊液漏是神经外科医生面临的主要问题之一，这是因为其在处理上偶尔存在困难，且后续感染具有灾难性后果。在脑脊液漏的外科治疗中出现的一种重要工具是纤维蛋白密封剂，即天然凝血产物。本文介绍了13例因脊髓脊膜膨出、创伤后及肿瘤继发导致的脑脊液漏，这些病例采用纤维蛋白密封剂进行了外科治疗。其中几例在传统手术技术失败后通过该方法成功完成手术。文中还讨论了纤维蛋白密封剂在神经外科的其他用途。
