Effect of ambient temperature on sleep-waking cycle in cats with electrolytic dorsolateral pontine tegmental lesions.

The effects of ambient temperature on the sleep-waking cycle were studied in intact cats and those with bilateral electrolytic lesions in the pontine tegmentum. At a room temperature of 23 degrees C, the percentage of time spent in paradoxical sleep was significantly lower in the lesioned cats than in intact animals. The mean duration of paradoxical sleep episodes was also decreased in the lesioned animals. The reduction in slow-wave sleep was not significant. At a slightly warmer ambient temperature of 30 degrees C, both the mean duration of paradoxical sleep episodes and the total duration of paradoxical sleep in the lesioned animals were increased toward normal values. Slow-wave sleep increased slightly but not significantly. At a higher ambient temperature of 35 degrees C, as well as at colder ambient temperatures of 15 and 7 degrees C, the durations of both paradoxical sleep and slow-wave sleep were significantly reduced. Under these thermal loads, the reduction in the duration of sleep was significantly greater in the lesioned cats than in the intact animals. The results suggest that: (i) pontine lesions alter the sleep cycle of cats and ambient temperature influences this alteration; (ii) the effects of thermal loads on the sleep cycle are more severe in the lesioned cats; and (iii) a moderately warm ambient temperature (30 degrees C) improves the sleep of pontine-lesioned cats.