Klein C, Wiese M, Rotzsch W
Bezirkslaboratorium für Klinische Chemie, Städtischen Klinikum St. George Leipzig.
Z Gesamte Inn Med. 1991 Dec;46(17):648-51.
The differentiation and classification of different types of viral hepatitis was essentially improved in the laboratory diagnosis by the direct determination of the virus in serum, viral antigens or their antibodies. Especially for the hepatitis B it is possible to recognize the infectivity by the serum marker HBeAg, the prognosis by seroconversion (HBeAg/HBeAb), the epidemiology, and vaccination prophylaxis, respectively. Without doubt, immunological marker have an increasing significance for prophylaxis, diagnosis, and therapy of viral hepatitis.
通过直接检测血清中的病毒、病毒抗原或其抗体,实验室诊断中不同类型病毒性肝炎的鉴别和分类有了实质性的改进。特别是对于乙型肝炎,分别可以通过血清标志物HBeAg识别传染性,通过血清转换(HBeAg/HBeAb)判断预后,了解流行病学情况以及进行疫苗预防。毫无疑问,免疫标志物在病毒性肝炎的预防、诊断和治疗中具有越来越重要的意义。