非妊娠女性阴道毛滴虫感染与阴道乳酸杆菌水平之间的关联。

The association between Trichomonas vaginalis infection and level of vaginal lactobacilli, in nonpregnant women.

作者信息

Torok Michelle R, Miller William C, Hobbs Marcia M, Macdonald Pia D M, Leone Peter A, Schwebke Jane R, Sena Arlene C

机构信息

Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

出版信息

J Infect Dis. 2007 Oct 1;196(7):1102-7. doi: 10.1086/521307. Epub 2007 Aug 23.

DOI:10.1086/521307

PMID:17763335

Abstract

The effect that vaginal lactobacilli have on trichomoniasis is not known. At 3 clinics for treatment of sexually transmitted disease, we recruited 521 female patients with trichomoniasis and 176 control subjects. All participants underwent physical examinations and testing for sexually transmitted infection and completed questionnaires. Low levels of vaginal lactobacilli were associated with trichomoniasis (odds ratio [OR], 2.2 [95% confidence interval {CI}, 1.4-3.2]). After adjustment for covariables, this association remained in women with a higher educational level (OR, 4.6 [95% CI, 2.2-9.5]) but not in women with a lower educational level (OR, 1.6 [95% CI, 0.7-3.4]). Vaginal lactobacilli may be associated with trichomoniasis in women with higher levels of education or a related behavioral factor.

摘要

阴道乳酸杆菌对滴虫病的影响尚不清楚。在3家性传播疾病治疗诊所，我们招募了521例患滴虫病的女性患者和176名对照对象。所有参与者均接受了体格检查和性传播感染检测，并完成了问卷调查。阴道乳酸杆菌水平低与滴虫病相关（比值比[OR]为2.2[95%置信区间{CI}为1.4 - 3.2]）。在对协变量进行校正后，这种关联在教育水平较高的女性中仍然存在（OR为4.6[95%CI为2.2 - 9.5]），但在教育水平较低的女性中不存在（OR为1.6[95%CI为0.7 - 3.4]）。阴道乳酸杆菌可能与教育水平较高或存在相关行为因素的女性的滴虫病有关。