Davanger M, Ringvold A, Blika S
Department of Ophthalmology, Rikshospitalet, Oslo, Norway.
Acta Ophthalmol (Copenh). 1991 Oct;69(5):569-73. doi: 10.1111/j.1755-3768.1991.tb04841.x.
On the basis of a glaucoma survey in a total population greater than or equal to 65 years of age, the IOP in eyes with and without pseudo-exfoliation (PE) has been compared. The average IOP was 22.2 mmHg in eyes with PE versus 17.4 in eyes without. The corresponding averages in eyes without glaucomatous damage were 18.6 and 17.1 mmHg, and in eyes with glaucoma 31.5 and 25.5 mmHg. The IOP elevation connected with the PE process was 4.8, 1.5, and 6.0 mmHg in the total, normal and glaucomatous population, respectively. The IOP frequency distribution curves of these 3 groups were compared. The right shift of the distribution curves of the PE groups was more pronounced at high pressure levels. The PE process seems to elevate the IOP particularly in eyes with a high IOP, which is in correspondence with hydrodynamical laws. At a certain IOP, the probability of having glaucomatous damage was higher in eyes with PE than in those without, indicating an increased vulnerability of PE eyes to an elevated IOP. PE may be a glaucoma risk factor also on its own, i.e. independent of the pressure elevation connected with this syndrome.
基于一项针对65岁及以上总人口的青光眼调查，对有和没有假性剥脱（PE）的眼睛的眼压进行了比较。有PE的眼睛平均眼压为22.2 mmHg，无PE的眼睛为17.4 mmHg。在没有青光眼损害的眼睛中，相应的平均值分别为18.6和17.1 mmHg，在患有青光眼的眼睛中为31.5和25.5 mmHg。在总人群、正常人群和青光眼人群中，与PE过程相关的眼压升高分别为4.8、1.5和6.0 mmHg。比较了这三组的眼压频率分布曲线。PE组分布曲线在高压水平时右移更为明显。PE过程似乎尤其会使眼压升高，在眼压高的眼睛中更是如此，这与流体动力学规律相符。在一定眼压下，有PE的眼睛发生青光眼损害的概率高于没有PE的眼睛，这表明有PE的眼睛对眼压升高的易损性增加。PE本身可能也是一个青光眼风险因素，即独立于与该综合征相关的眼压升高。
