Matsumoto T, Kuwabara N, Shiotsu H, Fukuda Y, Yanai A, Ichikawa G
First Department of Pathology, Juntendo University, School of Medicine, Tokyo, Japan.
Acta Pathol Jpn. 1991 Sep;41(9):689-93. doi: 10.1111/j.1440-1827.1991.tb02794.x.
Necrotizing sialometaplasia is a benign inflammatory process, which histologically can mimic squamous cell carcinoma. A 63-year-old man underwent left hemiglossectomy involving transplantation of a myocutaneous flap for squamous cell carcinoma of the tongue. One month after the operation, necrotizing sialometaplasia occurred in the minor salivary gland tissue of the mouth floor, compressed by the necrotic flap. This case is very unusual because of the occurrence of necrotizing sialometaplasia in the floor of the mouth. The etiology of the lesion was considered to be ischemia secondary to compression by the necrotic myocutaneous flap.
坏死性涎腺化生是一种良性炎症过程，在组织学上可酷似鳞状细胞癌。一名63岁男性因舌鳞状细胞癌接受了左半舌切除术，术中进行了肌皮瓣移植。术后1个月，口底小涎腺组织发生坏死性涎腺化生，该组织受到坏死皮瓣的压迫。由于口底发生坏死性涎腺化生，此病例非常罕见。病变的病因被认为是坏死性肌皮瓣压迫继发的缺血。
