Mesa M L, Gertler R S, Schneider L C
Oral Surg Oral Med Oral Pathol. 1984 Jan;57(1):71-3. doi: 10.1016/0030-4220(84)90264-0.
Necrotizing sialometaplasia is said to mimic carcinoma, both clinically and histologically. A review of approximately 10,000 oral biopsy specimens revealed only three cases of necrotizing sialometaplasia, all of which had been misdiagnosed as other benign entities. While this suggests that necrotizing sialometaplasia represents only 0.03 percent of biopsied oral lesions, it does not deal with the frequency of cases of this condition which heal spontaneously without being biopsied.
坏死性涎腺化生在临床和组织学上据说都可模拟癌。对大约10000份口腔活检标本的回顾显示,仅发现3例坏死性涎腺化生,所有这些病例均被误诊为其他良性病变。虽然这表明坏死性涎腺化生仅占活检口腔病变的0.03%,但它并未涉及这种疾病在未经活检而自发愈合的病例中的发生率。