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慢性光化性皮炎的外科治疗

Surgical management of chronic actinic dermatitis.

作者信息

Reichenberger M A, Stoff A, Richter D F

机构信息

Department of Plastic and Reconstructive Surgery, Dreifaltigkeits-Hospital, Bonner Strasse 84, 50389 Wesseling, Germany.

出版信息

J Plast Reconstr Aesthet Surg. 2008 Sep;61(9):e11-4. doi: 10.1016/j.bjps.2007.07.009. Epub 2007 Aug 31.

DOI:10.1016/j.bjps.2007.07.009
PMID:17765670
Abstract

Chronic actinic dermatitis (CAD) is a persistent, ultraviolet (UV) radiation-induced eczema by either UVA, UVB or visible light. We present the case of a 48-year-old woman suffering from severe CAD. Various therapeutic approaches, including topical and local corticosteroids and other systemic immunosuppressives, were used without success, making surgical treatment the only option. Two sessions of manual dermabrasion were necessary to improve the cutaneous disorder. We document the successful treatment of a severe case of CAD with dermabrasion. Chronic actinic dermatitis (CAD) describes a serious and persistent photoinduced skin disorder. It is usually characterised by a perennial, chronic dermatitis that predominantly affects sun-exposed sites, but may also affect shaded sites or even present as erythroderma. Daily application of sun protection has to be combined with topical and local corticosteroids and other systemic immunosuppressives. However, these various therapeutic regimens are often limited by severe side-effects and consecutive failure of therapy. [Dawe RS, Ferguson J. Diagnosis and treatment of chronic actinic dermatitis. Dermatol Ther 2003;16:45-51 [review], Hawk JL, Magnus IA. Chronic actinic dermatitis: an idiopathic photosensitivity syndrome including actinic reticuloid and photosensitive eczema [proceedings]. Br J Dermatol 1979;101(Suppl. 17):24.].

摘要

慢性光化性皮炎(CAD)是一种由UVA、UVB或可见光引起的持续性紫外线辐射诱发的湿疹。我们报告一例48岁患有严重CAD的女性病例。包括外用和局部使用皮质类固醇以及其他全身免疫抑制剂在内的各种治疗方法均未成功,使得手术治疗成为唯一选择。需要进行两期手动磨皮术来改善皮肤病症。我们记录了通过磨皮术成功治疗严重CAD病例的情况。慢性光化性皮炎(CAD)是一种严重且持续的光诱导性皮肤疾病。它通常表现为常年性慢性皮炎,主要累及暴露于阳光的部位,但也可能累及遮蔽部位甚至表现为红皮病。日常防晒必须与外用和局部皮质类固醇以及其他全身免疫抑制剂联合使用。然而,这些不同的治疗方案常常受到严重副作用和后续治疗失败的限制。[Dawe RS, Ferguson J.慢性光化性皮炎的诊断与治疗。皮肤病治疗学2003;16:45 - 51[综述],Hawk JL, Magnus IA.慢性光化性皮炎:一种包括光化性类网状细胞增生症和光敏性湿疹的特发性光敏综合征[会议论文集]。英国皮肤病学杂志1979;101(增刊17):24。]

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Surgical management of chronic actinic dermatitis.慢性光化性皮炎的外科治疗
J Plast Reconstr Aesthet Surg. 2008 Sep;61(9):e11-4. doi: 10.1016/j.bjps.2007.07.009. Epub 2007 Aug 31.
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Successful treatment of nodular actinic reticuloid with tacrolimus ointment.
Dermatology. 2006;212(4):377-80. doi: 10.1159/000092291.
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[Chronic actinic dermatitis. Concept and case examples].[慢性光化性皮炎。概念及病例示例]
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Actinic reticuloid--photosensitivity or pseudolymphoma?--A review.光化性类网状细胞增生症——光敏反应还是假性淋巴瘤?——综述
Coll Antropol. 2011 Sep;35 Suppl 2:325-9.
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[Chronic actinic dermatitis. Actinic reticuloid with transition to photosensitive eczema and return to actinic reticuloid].[慢性光化性皮炎。光化性类网状细胞增多症向光敏性湿疹转变并回归光化性类网状细胞增多症]
Med Cutan Ibero Lat Am. 1982;10(1):21-6.
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A case of chronic actinic dermatitis treated with topical tacrolimus.1例外用他克莫司治疗的慢性光化性皮炎
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Chronic photosensitivity.慢性光敏性
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