Dogan Ebru Apaydin, Yuruten Betigul
Selcuk University, Meram School of Medicine, Department of Neurology, Konya, Turkey.
Clin Neurol Neurosurg. 2007 Nov;109(9):827-9. doi: 10.1016/j.clineuro.2007.07.018. Epub 2007 Sep 4.
We report a 85-year-old female patient with involuntary and regular movements restricted to abdominal muscles, resembling belly dance, with additional clinical features; ataxia, impaired cognition, neuropathy and glossitis. We initially excluded the possible cortical and spinal structural abnormalities with magnetic resonance imagings and performed routine blood analysis which revealed that serum vitamin B12 (vB12) level was under normal ranges. The relation of low serum vB12 level and myoclonus is speculative and very few studies have demonstrated such patients. In this case report, serum vB12 deficiency is discussed in the context of its probable role in the generation of spinal myoclonus.
我们报告了一位85岁的女性患者,其腹部肌肉出现不自主且规律的运动,类似肚皮舞,还有其他临床特征,如共济失调、认知障碍、神经病变和舌炎。我们最初通过磁共振成像排除了可能的皮质和脊髓结构异常,并进行了常规血液分析,结果显示血清维生素B12(vB12)水平低于正常范围。血清vB12水平低与肌阵挛之间的关系尚属推测,且很少有研究报道过此类患者。在本病例报告中,我们将在血清vB12缺乏可能在脊髓肌阵挛发生中所起作用的背景下进行讨论。