Long X, Goss A N
Department of Oral and Maxillofacial Surgery, Key Lab for Oral Biomedical Engineering of Ministry of Education, School and Hospital of Stomatology, Wuhan University, PR China.
Int J Oral Maxillofac Surg. 2007 Sep;36(9):834-7. doi: 10.1016/j.ijom.2007.06.002. Epub 2007 Sep 4.
The aim of this study was to create in a sheep model an intracapsular oblique vertical split fracture, and observe the histopathological changes in the temporomandibular joint (TMJ) condylar head. In 10 sheep, the right TMJ was operated through the preauricular region. The anterior and posterior attachments of the disc were cut; an oblique vertical osteotomy was made from the lateral pole of the condyle to the medial side of condylar neck. The condylar fragment was pushed anteriorly, inferiorly and medially together with the disc. The non-operated left TMJ served as control. Two sheep were killed at 1 week and four at both 4 and 12 weeks. Computed tomography scans were taken and histopathological changes of the joint observed. There was severe bone erosion and a new bony outgrowth on the lateral side of the condylar stump and temporal bone. The joint spaces were filled with fibrous tissue, cartilage tissue and bone in the 4 and 12 weeks operated groups. These results show that an oblique vertical intracapsular fracture through the lateral condylar pole, combined with an anteriorly and medially displaced condylar fragment and disc and damaged lateral capsule, are likely to result in the pathological changes of osteoarthritis, and the progressive development of ankylosis in a sheep TMJ.
本研究的目的是在绵羊模型中制造囊内斜行垂直劈裂骨折，并观察颞下颌关节（TMJ）髁突头部的组织病理学变化。对10只绵羊的右侧颞下颌关节经耳前区域进行手术。切断盘的前后附着；从髁突外侧极至髁突颈部内侧进行斜行垂直截骨。将髁突碎片与盘一起向前、向下和向内推。未手术的左侧颞下颌关节作为对照。在1周时处死2只绵羊，在4周和12周时各处死4只绵羊。进行计算机断层扫描并观察关节的组织病理学变化。髁突残端外侧和颞骨出现严重骨质侵蚀及新骨增生。在4周和12周手术组中，关节间隙充满纤维组织、软骨组织和骨组织。这些结果表明，经外侧髁突极的囊内斜行骨折，合并髁突碎片和盘向前、向内移位以及外侧关节囊受损，可能导致绵羊颞下颌关节骨关节炎的病理变化以及关节强直的渐进性发展。
