Wu D, Yang X-J, Cheng P, Deng T-G, Jiang X, Liu P, Liu C-K, Meng F-W, Hu K-J
State Key Laboratory of Military Stomatology, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, China; Department of Stomatology, 152nd Hospital of the People's Liberation Army, Pingdingshan, China.
State Key Laboratory of Military Stomatology, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, China.
Int J Oral Maxillofac Surg. 2015 Aug;44(8):1010-5. doi: 10.1016/j.ijom.2015.02.004. Epub 2015 Mar 6.
The purpose of this study was to verify the role of the lateral pterygoid muscle in the reconstruction of the condyle shape during the sagittal fracture healing process by histological methods. Twenty-four adult sheep underwent an osteotomy to create a sagittal fracture of the left condyle; the sheep were then divided randomly into two groups. The lateral pterygoid muscles of the sheep in the experimental group were maintained on the internal poles of the condyles, and their functions remained stable. The lateral pterygoid muscles of the sheep in the control group were cut, and their functions were blocked. The shape, erosion, and calcification of the condyles were observed and measured after 4, 12, and 24 weeks of healing (n=4 from each group). The condyles were then submitted to haematoxylin and eosin, Ponceau S, and Sirius red studies. The results of the histology studies showed increased bone formation in the experimental group in which the functions of the lateral pterygoid muscle remained the same. The results of this study suggest that the lateral pterygoid muscle affects the reconstruction of the condylar shape during the healing process of a sagittal fracture of the mandibular condyle, and may even be involved in the formation of ankylosis.
本研究的目的是通过组织学方法验证翼外肌在下颌髁突矢状骨折愈合过程中对髁突形态重建的作用。24只成年绵羊接受截骨术以造成左侧髁突矢状骨折；然后将绵羊随机分为两组。实验组绵羊的翼外肌保留在髁突的内侧极，其功能保持稳定。对照组绵羊的翼外肌被切断，其功能被阻断。在愈合4周、12周和24周后观察并测量髁突的形态、侵蚀和钙化情况（每组4只）。然后对髁突进行苏木精-伊红染色、丽春红S染色和天狼星红染色研究。组织学研究结果显示，翼外肌功能保持不变的实验组骨形成增加。本研究结果表明，翼外肌在下颌髁突矢状骨折愈合过程中影响髁突形态的重建，甚至可能参与关节强直的形成。
