Moreno Carmen, Laje Gonzalo, Blanco Carlos, Jiang Huiping, Schmidt Andrew B, Olfson Mark
Unidad de Adolescentes, Hospital General Universitario Gregorio Marañón, Servicio do Psiquiatría, Madrid, Spain.
Arch Gen Psychiatry. 2007 Sep;64(9):1032-9. doi: 10.1001/archpsyc.64.9.1032.
CONTEXT: Although bipolar disorder may have its onset during childhood, little is known about national trends in the diagnosis and management of bipolar disorder in young people. OBJECTIVES: To present national trends in outpatient visits with a diagnosis of bipolar disorder and to compare the treatment provided to youth and adults during those visits. DESIGN: We compare rates of growth between 1994-1995 and 2002-2003 in visits with a bipolar disorder diagnosis by individuals aged 0 to 19 years vs those aged 20 years or older. For the period of 1999 to 2003, we also compare demographic, clinical, and treatment characteristics of youth and adult bipolar disorder visits. SETTING: Outpatient visits to physicians in office-based practice. PARTICIPANTS: Patient visits from the National Ambulatory Medical Care Survey (1999-2003) with a bipolar disorder diagnosis (n = 962). MAIN OUTCOME MEASURES: Visits with a diagnosis of bipolar disorder by youth (aged 0-19 years) and by adults (aged > or = 20 years). RESULTS: The estimated annual number of youth office-based visits with a diagnosis of bipolar disorder increased from 25 (1994-1995) to 1003 (2002-2003) visits per 100,000 population, and adult visits with a diagnosis of bipolar disorder increased from 905 to 1679 visits per 100,000 population during this period. In 1999 to 2003, most youth bipolar disorder visits were by males (66.5%), whereas most adult bipolar disorder visits were by females (67.6%); youth were more likely than adults to receive a comorbid diagnosis of attention-deficit/hyperactivity disorder (32.2% vs 3.0%, respectively; P < .001); and most youth (90.6%) and adults (86.4%) received a psychotropic medication during bipolar disorder visits, with comparable rates of mood stabilizers, antipsychotics, and antidepressants prescribed for both age groups. CONCLUSIONS: There has been a recent rapid increase in the diagnosis of youth bipolar disorder in office-based medical settings. This increase highlights a need for clinical epidemiological reliability studies to determine the accuracy of clinical diagnoses of child and adolescent bipolar disorder in community practice.
背景:尽管双相情感障碍可能在儿童期发病,但对于年轻人双相情感障碍诊断和管理的全国趋势知之甚少。 目的:呈现诊断为双相情感障碍的门诊就诊的全国趋势,并比较就诊期间为青少年和成年人提供的治疗。 设计:我们比较了1994 - 1995年和2002 - 2003年0至19岁个体与20岁及以上个体诊断为双相情感障碍的就诊增长率。在1999年至2003年期间,我们还比较了青少年和成人双相情感障碍就诊的人口统计学、临床和治疗特征。 地点:基于办公室执业的医生的门诊就诊。 参与者:来自国家门诊医疗护理调查(1999 - 2003年)诊断为双相情感障碍的患者就诊(n = 962)。 主要观察指标:青少年(0 - 19岁)和成年人(年龄≥20岁)诊断为双相情感障碍的就诊情况。 结果:每10万人口中,估计诊断为双相情感障碍的青少年门诊就诊年度数量从1994 - 1995年的25次增加到2002 - 2003年的1003次,在此期间,诊断为双相情感障碍的成人就诊从每10万人口905次增加到1679次。在1999年至2003年期间,大多数青少年双相情感障碍就诊者为男性(66.5%),而大多数成人双相情感障碍就诊者为女性(67.6%);青少年比成年人更有可能同时被诊断为注意力缺陷/多动障碍(分别为32.2%和3.0%;P <.001);大多数青少年(90.6%)和成年人(86.4%)在双相情感障碍就诊期间接受了精神药物治疗,两个年龄组开具心境稳定剂、抗精神病药物和抗抑郁药物的比例相当。 结论:近期在基于办公室的医疗环境中,青少年双相情感障碍的诊断迅速增加。这一增加凸显了开展临床流行病学可靠性研究以确定社区实践中儿童和青少年双相情感障碍临床诊断准确性的必要性。
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