Arnold Raoul, Ley Sebastian, Ley-Zaporozhan Julia, Eichhorn Joachim, Schenk Jens-Peter, Ulmer Herbert, Kauczor Hans-Ulrich
Department of Paediatric Cardiology, University Hospital, Heidelberg, Germany.
Pediatr Radiol. 2007 Oct;37(10):998-1006. doi: 10.1007/s00247-007-0566-2. Epub 2007 Sep 1.
After childhood Kawasaki syndrome (KS) the coronary arteries undergo a lifelong dynamic pathological change, and follow-up coronary artery imaging is essential. At present, conventional coronary catheterization (CCC) and angiography is still regarded as the gold standard. Less-invasive methods such as multidetector CT angiography (MDCT-A) and MRI have been used sporadically.
To compare the diagnostic quality of MDCT-A and MRI with that of CCC for coronary imaging in a group of patients with coronary artery pathology after childhood KS.
A total of 16 patients (aged 5-27 years) underwent CCC and 16-row MDCT-A and 14 patients MRI (1.5 T).
There was 100% agreement between MDCT-A and CCC in the detection of coronary aneurysms and stenoses. MDCT-A was superior for the visualization of calcified lesions. MRI and CCC showed 93% agreement for the detection of aneurysms. Visualization of coronary artery stenoses was difficult using MRI-one stenosis was missed.
MDCT-A has excellent correlation with CCC regarding all changes affecting the coronary arteries in the follow-up of childhood KS. In comparison to MDCT-A and CCC, MRI is less precise in the detection of stenotic lesions. Due to its high image quality and ease of performance MDCT-A should be the primary diagnostic modality in patients following childhood KS.
儿童期川崎病(KS)后,冠状动脉会经历终身动态病理变化,因此冠状动脉随访成像至关重要。目前,传统冠状动脉导管插入术(CCC)和血管造影仍被视为金标准。多排CT血管造影(MDCT-A)和MRI等侵入性较小的方法已偶尔使用。
比较MDCT-A和MRI与CCC对一组儿童期KS后冠状动脉病变患者进行冠状动脉成像的诊断质量。
共有16例患者(年龄5 - 27岁)接受了CCC、16排MDCT-A检查,14例患者接受了MRI(1.5T)检查。
MDCT-A与CCC在检测冠状动脉瘤和狭窄方面的一致性为100%。MDCT-A在显示钙化病变方面更具优势。MRI与CCC在检测动脉瘤方面的一致性为93%。使用MRI很难观察到冠状动脉狭窄——漏诊了一处狭窄。
在儿童期KS随访中,MDCT-A与CCC在影响冠状动脉的所有变化方面具有极好的相关性。与MDCT-A和CCC相比,MRI在检测狭窄病变方面不够精确。由于其高图像质量和操作简便,MDCT-A应成为儿童期KS患者的主要诊断方式。