Lefebure B, Tuech J J, Bridoux V, Costaglioli B, Scotte M, Teniere P, Michot F
Department of Digestive Surgery, Rouen University Hospital, Rouen Cedex 76031, France.
Int J Colorectal Dis. 2008 Mar;23(3):283-8. doi: 10.1007/s00384-007-0380-1. Epub 2007 Sep 2.
Anastomotic leakage is a major concern after resection for low rectal cancer. Therefore, the use of a defunctioning stoma (DS) has been suggested, but limited data exist to clearly determine the necessity of a routine diversion. In our department, the indication of DS was evaluated subjectively by the operating surgeon. The aim of this study was to evaluate the selective use of fecal diversion.
Retrospective chart review of patients who underwent low anterior resection for carcinoma was performed. The incidence and consequences of clinical leaks were determined in these patients who were considered in two groups: defunctioning stoma and no defunctioning stoma.
From 1995 to 2005, 132 consecutive patients underwent low anterior resection; a DS was performed in 42 patients (31.8%). Median level of anastomosis was 4 cm in both groups. Overall clinical leakage rate was 9.8%: 7.1% (n = 3) with a DS and 11% (n = 10) without a stoma. Mortality rate was 1.5% (n = 2), both in the unprotected group. No patient in the diversion group required a permanent stoma, contrasting with four unprotected patients in which continuity could not be restored after break down of the anastomosis.
Finding lower clinical leakage rate in a probable higher risk group and better outcome when a leak occurs in our study constituted strong evidence of the effectiveness of a DS. Selective use of a DS based on subjective assessment at the time of surgery could not allow experienced surgeons to perform single-stage procedure safely. Construction of a DS seems useful for patients with distal rectal cancer.
低位直肠癌切除术后,吻合口漏是一个主要问题。因此,有人建议使用去功能化造口(DS),但目前明确确定常规造口必要性的数据有限。在我们科室,DS的指征由手术医生主观评估。本研究的目的是评估粪便转流的选择性应用。
对接受低位前切除术治疗癌症的患者进行回顾性病历审查。在这些患者中确定临床漏的发生率和后果,这些患者被分为两组:去功能化造口组和非去功能化造口组。
1995年至2005年,132例连续患者接受了低位前切除术;42例患者(31.8%)进行了DS。两组的吻合口中位水平均为4cm。总体临床漏率为9.8%:DS组为7.1%(n = 3),无造口组为11%(n = 10)。死亡率为1.5%(n = 2),均在未行保护措施的组中。转流组无患者需要永久性造口,相比之下,未行保护措施的组中有4例患者在吻合口破裂后无法恢复肠道连续性。
在本研究中,在可能的高风险组中发现较低的临床漏率以及漏发生时更好的结果,构成了DS有效性的有力证据。基于手术时主观评估选择性使用DS不能让经验丰富的外科医生安全地进行一期手术。对于低位直肠癌患者,构建DS似乎是有用的。