肯尼亚一种引起绵羊和山羊痘病的病毒特性，以及关于流行病学和防控的观察
Characteristics of a virus causing a pox disease in sheep and goats in Kenya, with observation on the epidemiology and control.
作者信息
Davies F G
出版信息
J Hyg (Lond). 1976 Apr;76(2):163-71. doi: 10.1017/s0022172400055066.
Abstract
The sheep and goat pox viruses isolated in Kenya are not host specific as in the Middle East and India. The virus strains from one species are of a similar pathogenicity for the other, and the same virus appears to occur in the field outbreaks in mixed flocks. A silent infection with no skin lesions occurs in the field outbreaks. The virus grows well in lamb testis cell cultures, it does not haemadsorb nor haemagglutinate and is ether sensitive. Most strains could not readily be adapted to grow on the chorioallantoic membrane of embryonated eggs; one isolation only was made in this way. Staining of the virus inclusions showed that they were of DNA; the virus resembled that of lumpy skin disease in many characteristics. It was possible to cross-protect both species with virus of sheep or goat origin. A vaccine was made from tissue culture virus adsorped onto aluminium hydroxide gel and treated with formalin.
摘要
在肯尼亚分离出的绵羊痘病毒和山羊痘病毒不像中东和印度那样具有宿主特异性。来自一个物种的病毒株对另一个物种具有相似的致病性，并且在混合羊群的野外疫情中似乎出现了相同的病毒。在野外疫情中会发生无皮肤病变的隐性感染。该病毒在羔羊睾丸细胞培养物中生长良好，不发生血细胞吸附和血细胞凝集，且对乙醚敏感。大多数毒株不易适应在鸡胚绒毛尿囊膜上生长；仅通过这种方式进行了一次分离。病毒包涵体的染色显示它们是DNA；该病毒在许多特征上类似于结节性皮肤病病毒。用绵羊或山羊来源的病毒对两个物种进行交叉保护是可行的。一种疫苗是由吸附在氢氧化铝凝胶上并用福尔马林处理的组织培养病毒制成的。
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