Kolesnichenko T S, Antoshina E E
Biull Eksp Biol Med. 1991 Dec;112(12):633-5.
The dynamics of proliferative activity of cells was studied in the cultures of organotypic recombinants obtained from embryonic lung epithelium (E) and mesenchyma (M) of the intact and treated transplacentally by urethane mice (strain A). The labelling index (LI) of E and M in the aggregates obtained from treated embryonic lungs (EtMt) was significantly higher than LI in the aggregates from intact embryonic lungs (EiMi) in all days of cultivation (4-7-14). M from the treated embryonic lungs stimulated LI of the intact E (EiMt) but M from the intact embryonic lungs decreased LI of the treated E (EtMi).
在从完整的以及经氨基甲酸乙酯经胎盘处理的小鼠(A品系)的胚胎肺上皮(E)和间充质(M)获得的器官型重组体培养物中,研究了细胞增殖活性的动态变化。在培养的所有天数(4 - 7 - 14天)中,从经处理的胚胎肺获得的聚集体(EtMt)中E和M的标记指数(LI)显著高于从完整胚胎肺获得的聚集体(EiMi)中的LI。来自经处理胚胎肺的M刺激完整E(EiMt)的LI,但来自完整胚胎肺的M降低经处理E(EtMi)的LI。