Y染色体多态性确定了莽族的起源，莽族是中国一个与世隔绝的群体。
Y-chromosome polymorphisms define the origin of the Mang, an isolated population in China.
作者信息
Tan Sijie, Yang Minhui, Yu Haijing, Dong Yongli, Shou Weihua, Zou Ju, Tang Wenru, Guo Yue, Xiao Chunjie
机构信息
Key Laboratory of Bioresources Conservation and Utilization & Human Genetics Center, Yunnan University, PR China.
出版信息
Ann Hum Biol. 2007 Sep-Oct;34(5):573-81. doi: 10.1080/03014460701492237.
The Mang is an isolated population living at the border of Vietnam and China characterized by small stature and a primordial lifestyle. However, the origin of this population remains unclear. To clarify the origin of the Mang and its genetic relationship with other populations, 20 Y-chromosome markers were analyzed, including 12 biallelic markers and eight short tandem repeats (STR) in this population, and the data compared with published data from other populations in eastern Asia. Only three Y-chromosome haplogroups, O2a*-M95, O3d-M7 and O3e-M134, were identified in Mang. Among them, the southern haplogroups O2a*-M95 were most prevalent, with a frequency of 97%. Principal component analysis (PCA) plots showed that Mang clustered with southern populations but not with northern populations. In conclusion, the present study provided evidence for the first time that the Mang population is of southern origin.
莽人是生活在越南和中国边境的一个孤立群体，其特征是身材矮小和保留着原始的生活方式。然而，这个群体的起源仍不清楚。为了阐明莽人的起源及其与其他群体的遗传关系，对该群体的20个Y染色体标记进行了分析，包括12个双等位基因标记和8个短串联重复序列（STR），并将数据与东亚其他群体已发表的数据进行比较。在莽人中仅鉴定出三个Y染色体单倍群，即O2a*-M95、O3d-M7和O3e-M134。其中，南方单倍群O2a*-M95最为普遍，频率为97%。主成分分析（PCA）图显示，莽人与南方群体聚类，而不与北方群体聚类。总之，本研究首次提供证据表明莽人群体起源于南方。
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