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中国揭阳汉族人群 23 个 Y-STR 基因座分析。

Analysis of 23 Y-STR loci in Chinese Jieyang Han population.

机构信息

School of Forensic Medicine, Southern Medical University, Guangzhou, 510515, China.

Department of Endocrinology, The First Affiliated Hospital of Guangdong Pharmaceutical College, Guangzhou, 510080, China.

出版信息

Int J Legal Med. 2020 Mar;134(2):505-507. doi: 10.1007/s00414-019-02019-y. Epub 2019 Feb 18.

DOI:10.1007/s00414-019-02019-y
PMID:30778658
Abstract

Genetic polymorphisms of 23 Y-chromosomal short tandem repeats (Y-STR) were investigated by PowerPlex® Y23 System in 328 unrelated male participants from Jieyang, Guangdong Province of China. A total of 293 haplotypes were obtained, and the haplotype diversity (HD) and discrimination capacity (DC) were 0.9991 and 0.8933, respectively. By comparing Jieyang population with nine other populations, Jieyang Han showed close genetic relationships with southern China-related Han populations. In conclusion, our study increased the Y-chromosome haplotype reference database and could provide useful information for forensic investigation and population genetics.

摘要

对 328 名来自中国广东省揭阳市的无关男性个体的 23 个 Y 染色体短串联重复序列(Y-STR)的遗传多态性进行了研究,使用的是 PowerPlex® Y23 系统。共获得 293 种单倍型,单倍型多样性(HD)和判别能力(DC)分别为 0.9991 和 0.8933。通过将揭阳市人群与其他 9 个人群进行比较,揭阳市汉族与中国南方汉族人群具有密切的遗传关系。总之,本研究增加了 Y 染色体单倍型参考数据库,可为法医学调查和群体遗传学提供有用的信息。

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本文引用的文献

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A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.23 个 STR 基因座的 Y 染色体单倍型多样性的全球分析。
Forensic Sci Int Genet. 2014 Sep;12(100):12-23. doi: 10.1016/j.fsigen.2014.04.008. Epub 2014 Apr 28.
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Update of the guidelines for the publication of genetic population data.遗传群体数据发布指南的更新
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Developmental validation of the PowerPlex® Y23 System: a single multiplex Y-STR analysis system for casework and database samples.
基于27个Y染色体短串联重复序列对广东茂名汉族人群法医学特征及遗传结构的研究
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Insights From Y-STRs: Forensic Characteristics, Genetic Affinities, and Linguistic Classifications of Guangdong Hakka and She Groups.Y染色体短串联重复序列的见解:广东客家和畲族群体的法医特征、遗传亲缘关系及语言分类
Front Genet. 2021 May 24;12:676917. doi: 10.3389/fgene.2021.676917. eCollection 2021.
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