居住在川西走廊的羌语支人群的遗传结构。
Genetic structure of Qiangic populations residing in the western Sichuan corridor.
作者信息
Wang Chuan-Chao, Wang Ling-Xiang, Shrestha Rukesh, Zhang Manfei, Huang Xiu-Yuan, Hu Kang, Jin Li, Li Hui
机构信息
State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Key Laboratory of High Altitude Environment and Genes Related to Diseases of Tibet Autonomous Region, School of Medicine, Tibet University for Nationalities, Xianyang, Shaanxi, China.
出版信息
PLoS One. 2014 Aug 4;9(8):e103772. doi: 10.1371/journal.pone.0103772. eCollection 2014.
The Qiangic languages in western Sichuan (WSC) are believed to be the oldest branch of the Sino-Tibetan linguistic family, and therefore, all Sino-Tibetan populations might have originated in WSC. However, very few genetic investigations have been done on Qiangic populations and no genetic evidences for the origin of Sino-Tibetan populations have been provided. By using the informative Y chromosome and mitochondrial DNA (mtDNA) markers, we analyzed the genetic structure of Qiangic populations. Our results revealed a predominantly Northern Asian-specific component in Qiangic populations, especially in maternal lineages. The Qiangic populations are an admixture of the northward migrations of East Asian initial settlers with Y chromosome haplogroup D (D1-M15 and the later originated D3a-P47) in the late Paleolithic age, and the southward Di-Qiang people with dominant haplogroup O3a2c1*-M134 and O3a2c1a-M117 in the Neolithic Age.
川西的羌语支语言被认为是汉藏语系中最古老的分支，因此，所有汉藏语系人群可能都起源于川西。然而，针对羌语支人群的遗传学研究极少，也没有提供关于汉藏语系人群起源的遗传学证据。通过使用信息丰富的Y染色体和线粒体DNA（mtDNA）标记，我们分析了羌语支人群的遗传结构。我们的结果显示，羌语支人群中主要是北亚特异性成分，尤其是在母系血统中。羌语支人群是旧石器时代晚期东亚初始定居者携带Y染色体单倍群D（D1-M15和后来起源的D3a-P47）向北迁移，以及新石器时代携带主要单倍群O3a2c1*-M134和O3a2c1a-M117的氐羌人群向南迁移后的混合群体。
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