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关于经济评估中的未来非医疗成本。

On future non-medical costs in economic evaluations.

作者信息

Liljas Bengt, Karlsson Göran S, Stålhammar Nils-Olov

机构信息

AstraZeneca, Mölndal, Sweden.

出版信息

Health Econ. 2008 May;17(5):579-91. doi: 10.1002/hec.1279.

Abstract

Economic evaluation in health care is still an evolving discipline. One of the current controversies in cost-effectiveness analysis regards the inclusion or exclusion of future non-medical costs (i.e. consumption net of production) due to increased survival. This paper examines the implications of a symmetry rule stating that there should be consistency between costs included in the numerator and utility aspects included in the denominator. While the observation that no quality-adjusted life year (QALY) instruments explicitly include consumption and leisure seems to give support to the notion that future non-medical costs should be excluded when QALYs are used as the outcome measure, a better understanding of what respondents actually consider when reporting QALY weights is required. However, the more fundamental question is whether QALYs can be interpreted as utilities. Or more precisely, what are the assumptions needed for a general utility model also including consumption and leisure to be consistent with QALYs? Once those assumptions are identified, they need to be experimentally tested to see whether they are at least approximately valid. Until we have answers to these areas for future research, it seems premature to include future non-medical costs.

摘要

医疗保健领域的经济评估仍是一门不断发展的学科。成本效益分析当前的争议之一在于,因生存率提高而产生的未来非医疗成本(即生产净值后的消费)是否应纳入考量。本文探讨了一项对称性规则的影响,该规则指出分子中包含的成本与分母中包含的效用方面应保持一致。虽然观察到没有质量调整生命年(QALY)工具明确纳入消费和休闲,这似乎支持了在将QALY用作结果指标时应排除未来非医疗成本的观点,但需要更好地理解受访者在报告QALY权重时实际考虑的因素。然而,更根本的问题是QALY是否可以被解释为效用。或者更确切地说,一个也包括消费和休闲的通用效用模型要与QALY一致需要哪些假设?一旦确定了这些假设,就需要通过实验进行检验,看它们是否至少大致有效。在我们对这些未来研究领域有答案之前,纳入未来非医疗成本似乎为时过早。

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