Blansjaar B A, Zwang R, Blijenberg B G
Joris Psychiatric Centre, St. Joris Gasthuis, Delft, The Netherlands.
J Neurol Sci. 1991 Nov;106(1):88-90. doi: 10.1016/0022-510x(91)90199-h.
Transketolase isoenzyme patterns of Wernicke-Korsakoff patients, relatives, alcoholics and controls, obtained by isoelectric focusing of purified erythrocyte transketolase, were all identical. After a series of investigations published by several authors little evidence remains to support the hypothesis of an inborn transketolase abnormality in Wernicke-Korsakoff patients.
通过对纯化的红细胞转酮醇酶进行等电聚焦获得的韦尼克-科尔萨科夫综合征患者、其亲属、酗酒者和对照组的转酮醇酶同工酶模式均相同。在几位作者发表了一系列研究之后,几乎没有证据支持韦尼克-科尔萨科夫综合征患者存在先天性转酮醇酶异常这一假说。