Mariani C, Cislaghi M G, Barbieri S, Filizzolo F, Di Palma F, Farina E, D'Aliberti G, Scarlato G
Institute of Clinical Neurology, University of Milan, Italy.
J Neurol. 1991 Dec;238(8):433-8. doi: 10.1007/BF00314649.
In recent years, new neuroimaging techniques have revived interest in syringomyelia with respect to indications and results of surgery. Fifty patients, 36 of whom underwent surgery, have been reviewed. All patients but 3 underwent a new clinical assessment and 33 of them were also neurophysiologically investigated. In approximately one-third of the non-surgically treated patients the clinical course was benign. In 26 of the surgically treated patients an improvement was noted at the short-term assessment both for spasticity and pain, but in most of them it was not maintained in the medium term. Therefore, an accurate selection of the patients to be treated surgically is strongly recommended, particularly when the natural history of the disease is considered. Decompression of the posterior fossa seems to give the best results, yet no curative surgical treatment has been devised to date.
近年来，新的神经影像学技术重新唤起了人们对脊髓空洞症手术适应证和手术效果的兴趣。我们回顾了50例患者，其中36例接受了手术。除3例患者外，所有患者均接受了新的临床评估，其中33例还进行了神经生理学检查。在大约三分之一未接受手术治疗的患者中，临床病程呈良性。在26例接受手术治疗的患者中，短期评估时痉挛和疼痛均有改善，但大多数患者在中期并未维持这种改善。因此，强烈建议准确选择手术治疗的患者，尤其是考虑到疾病的自然病程时。后颅窝减压似乎能取得最佳效果，但迄今为止尚未设计出治愈性的手术治疗方法。
