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关于脊髓空洞症发病机制的一些观察

Some observations on the pathogenesis of syringomyelia.

作者信息

Newman P K, Terenty T R, Foster J B

出版信息

J Neurol Neurosurg Psychiatry. 1981 Nov;44(11):964-9. doi: 10.1136/jnnp.44.11.964.

Abstract

The pathogenesis of most cases of syringomyelia remains obscure although a modification of the hydrodynamic theory of Gardner allows a logical surgical approach to treatment. Data are presented confirming a high incidence of traumatic birth in patients with syringomyelia who have a Chiari malformation or basal arachnoiditis, but demonstrating no increase in traumatic birth in patients with the Chiari malformation but no syringomyelia. A traumatic birth may be the factor responsible for creating the potential for syringomyelia in those individuals with the embryological defect of the Chiari anomaly.

摘要

尽管Gardner流体动力学理论的修正为治疗脊髓空洞症提供了合理的手术方法,但大多数脊髓空洞症病例的发病机制仍不清楚。数据表明,患有Chiari畸形或基底蛛网膜膜炎的脊髓空洞症患者中,产伤发生率很高,但Chiari畸形但无脊髓空洞症的患者中产伤并未增加。产伤可能是导致那些患有Chiari异常胚胎学缺陷的个体发生脊髓空洞症的潜在因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cd3/491199/4dedd2e28b4b/jnnpsyc00067-0012-a.jpg

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