Science. 1968 Feb 16;159(3816):745-6. doi: 10.1126/science.159.3816.745.
When cats are subjected to an atmosphere of 100 percent oxygen at a sufficiently low pressure, their sleeping patterns are changed: paradoxical sleep disappears and drowsiness increases. This change appears when the pressure decreases to a level close to that at which the hemoglobin begins to dissociate. Return of a cat to a normal atmosphere produces a rebound: the cat spends more time in paradoxical sleep than it did during the base-line period. This finding suggests that a mechanism, closely related to the metabolism of oxygen in the brain, must play an important role in the production of paradoxical sleep. Yet the increase in paradoxical sleep after decompression indicates that still other mechanisms must merge to produce paradoxical sleep.
当猫处于足够低的压力下的 100%氧气环境中时，它们的睡眠模式会发生变化：异相睡眠消失，嗜睡增加。这种变化发生在压力降低到接近血红蛋白开始解离的水平时。猫回到正常大气中会产生反弹：猫在异相睡眠中花费的时间比基线期多。这一发现表明，一种与大脑中氧气代谢密切相关的机制，必须在异相睡眠的产生中发挥重要作用。然而，减压后异相睡眠的增加表明，其他机制也必须合并才能产生异相睡眠。
