在富氧环境中劳斯肉瘤病毒感染的而非正常的鸡成纤维细胞的增殖：初步报告
Proliferation of Rous sarcoma virus-infected, but not of normal, chicken fibroblasts in oxygen-enriched environment: preliminary report.
作者信息
Mitchell R S, Elgas R J, Balk S D
出版信息
Proc Natl Acad Sci U S A. 1976 Apr;73(4):1265-8. doi: 10.1073/pnas.73.4.1265.
Abstract
Both normal and Rous sarcoma virus-infected chicken fibroblasts proliferate in an incubator containing 95% air, 5% CO2. In an incubator atmosphere enriched with oxygen, however, the normal fibroblasts are maintained without proliferation, while the Rous sarcoma virus-infected fibroblasts continue to proliferate. This suggests that a respiratory function may be involved in the regulation of proliferation of normal cells, and that neoplastic cells may proliferate autonomously because of a deficiency in this regulatory function.
摘要
正常的和感染劳氏肉瘤病毒的鸡成纤维细胞都能在含有95%空气和5%二氧化碳的培养箱中增殖。然而，在富含氧气的培养箱环境中，正常成纤维细胞保持不增殖状态，而感染劳氏肉瘤病毒的成纤维细胞则继续增殖。这表明呼吸功能可能参与正常细胞增殖的调节，并且肿瘤细胞可能由于这种调节功能的缺陷而自主增殖。
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Proliferation of Rous sarcoma virus-infected, but not of normal, chicken fibroblasts in oxygen-enriched environment: preliminary report.在富氧环境中劳斯肉瘤病毒感染的而非正常的鸡成纤维细胞的增殖：初步报告
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Active proliferation of Rous sarcoma virus-infected, but not normal, chicken heart mesenchymal cells in culture medium of physiological composition.在生理成分培养基中，劳斯肉瘤病毒感染的鸡心脏间充质细胞（而非正常细胞）的活跃增殖。
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Proliferation of Rous sarcoma virus-infected, but not of normal, chicken fibroblasts in a medium of reduced calcium and magnesium concentration.劳氏肉瘤病毒感染的鸡成纤维细胞（而非正常鸡成纤维细胞）在钙和镁浓度降低的培养基中增殖。
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On the origin of cancer cells.论癌细胞的起源。
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A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro.一种依赖血小板的血清因子，可在体外刺激动脉平滑肌细胞增殖。
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The failure of methotrexate to inhibit chicken fibroblast proliferation in a serum-containing culture medium.
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Induction of growth in resting fibroblastic cell cultures by Ca++.钙离子诱导静止成纤维细胞培养物生长。
Proc Natl Acad Sci U S A. 1975 Apr;72(4):1584-8. doi: 10.1073/pnas.72.4.1584.
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