Krivorutchenko Iu L, Krivoshein Iu S, Andronovskaia I B, Kastrikina L N, Lonskaia N I, Rud'ko A P
Mikrobiol Zh (1978). 1991 May-Jun;53(3):96-100.
Native detergents, desintegron-O-and desintegron-B, solubilize hemagglutinins of the influenza virus as intensively, as foreign drugs (mulgophen, zwittergent and sodium sarcozyl) do. This permits recommending desintegrons for quantitative determination of hemagglutinin of the influenza virus in virus-containing materials by means of the reaction of single radial immunodiffusion. Desintegron-O and desintegron-B permit extracting enzymatically active neuraminidase from influenza A viruses with 44.6-83.4% yield.
天然去污剂去整合素-O和去整合素-B对流感病毒血凝素的增溶作用与外来药物（多聚酚、两性离子去污剂和N-月桂酰肌氨酸钠）一样强烈。这使得去整合素可用于通过单向辐射免疫扩散反应对含病毒材料中的流感病毒血凝素进行定量测定。去整合素-O和去整合素-B能以44.6% - 83.4%的产率从甲型流感病毒中提取具有酶活性的神经氨酸酶。
