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Hypothalamic and pituitary effects of prostaglandins on ACTH secretion.

作者信息

Hedge G A

出版信息

Prostaglandins. 1976 Feb;11(2):293-301. doi: 10.1016/0090-6980(76)90152-0.

DOI:10.1016/0090-6980(76)90152-0
PMID:178029
Abstract

Various prostaglandins (PGs) were tested for their effects on ACTH secretion upon injection into the anterior pituitary, basomedial hypothalamus, basolateral hypothalamus, or a tail vein in anesthetized female rats. In some experiments, the PGs were injected in combination with a CRF preparation. The greatest effect seen was the stimulation of ACTH (and presumably CRF) secretion exerted at the basomedial hypothalamus. At the anterior pituitary, the PGs alone were without effect, but they did decrease the magnitude of the response to subsequent CRF.

摘要

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引用本文的文献

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Br J Pharmacol. 2002 Apr;135(8):1851-8. doi: 10.1038/sj.bjp.0704652.
2
Immunomodulatory peptides and the central nervous system.
Springer Semin Immunopathol. 1985;8(1-2):153-64. doi: 10.1007/BF00197253.
3
Effect of prostaglandin E2 on ACTH and beta-endorphin release from rat adenohypophysis in vitro after secretagogues which can mimic various first or second messengers.在体外，前列腺素E2对促肾上腺皮质激素（ACTH）和β-内啡肽从大鼠腺垂体释放的影响，这些促分泌素可模拟各种第一或第二信使。
Naunyn Schmiedebergs Arch Pharmacol. 1986 Jun;333(2):149-55. doi: 10.1007/BF00506518.
4
Ultrastructure and morphometry of ACTH-producing cell in the rat anterior pituitary gland stimulated by lysin-vasopressin and prostaglandin E1.赖氨酸加压素和前列腺素E1刺激下大鼠垂体前叶促肾上腺皮质激素分泌细胞的超微结构及形态测定
Virchows Arch A Pathol Anat Histol. 1978 May 5;378(1):23-33. doi: 10.1007/BF00427183.