妊娠与肝脏疾病

Pregnancy and liver disease.

作者信息

Asimuakopoulos G

机构信息

Ammerland Klinik Westerstede, Department of Obstetrics and Gynecology.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2006 Apr-Jun;110(2):326-33.

PMID:17802941

Abstract

Liver dysfunction can appear at any point of pregnancy and causes great anxiety to the patient, her family and sometimes her medical attendants. This review concentrates on conditions specific to pregnancy (hyperemesis gravidarum, intrahepatic cholestasis of pregnancy, toxemia of pregnancy, HELLP syndrome) and provides a guide in diagnosis and management of hepatobiliary conditions that are probably related to pregnancy (e.g., gallstones, Budd-Chiari syndrome) or that are not specific to pregnancy (e.g., acute viral hepatitis), and also the situations in which pregnancy occurs during pre-existing liver disease (e.g., chronic active hepatitis, cirrhosis, Dubin-Johnson syndrome, Wilson's disease).

摘要

肝功能障碍可在孕期任何时候出现，会让患者、其家人乃至有时其医护人员极为焦虑。本综述聚焦于孕期特有的情况（妊娠剧吐、妊娠期肝内胆汁淤积症、妊娠中毒症、HELLP综合征），并为可能与妊娠相关的肝胆疾病（如胆结石、布加综合征）或非孕期特有的疾病（如急性病毒性肝炎）的诊断和管理提供指南，同时也涉及在已有肝病（如慢性活动性肝炎、肝硬化、杜宾-约翰逊综合征、威尔逊病）期间发生妊娠的情况。