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[应用脉冲多普勒评估阻塞性肺病患者的肺动脉压]

[The assessment of pulmonary arterial pressure by pulsed Doppler in patients with obstructive pneumopathy].

作者信息

Corinaldesi A, Zompatori M, Sturani C, Rimondi M R, Fasano L, Scarduelli C

机构信息

Istituto di Radiologia, Università, Policlinico S. Orsola, Bologna.

出版信息

Radiol Med. 1991 Nov;82(5):589-95.

PMID:1780455
Abstract

The severity of pulmonary arterial hypertension can be assessed by duplex-Doppler echocardiography, a subxiphoid approach and a general-purpose duplex device. Normally, the peak Doppler flow velocity occurs in midsystole and the flow profile is parabolic (bullet-like). In pulmonary arterial hypertension, changes in vascular compliance cause maximal acceleration of blood in early systole, with shortening of pulmonary acceleration time (AcT, or time to peak velocity). In the more severe cases, a midsystolic notching is visible, related to rapid deceleration of blood flow, followed by a brief secondary increase in velocity in the late systole. We studied 19 adult patients with chronic obstructive pulmonary disease with duplex-Doppler examination, with a subxiphoid approach and right heart catheterization. The study was diagnostic in all cases with Doppler recordings of good quality. An relationship was found between AcT and pulmonary mean or systolic arterial pressure at rest. An evident accurate prediction of pulmonary arterial pressure in emphysematous patients is possible by means of pulsed Doppler, also in case of low-level hypertension. We believe this method to be a simple and reliable adjunct to the non-invasive work-up of emphysematous patients and to represent a good alternative to the classical parasternal approach, which is often not feasible in these patients.

摘要

肺动脉高压的严重程度可通过双功多普勒超声心动图、剑突下途径和通用双功设备进行评估。正常情况下,多普勒血流峰值速度出现在收缩中期,血流形态呈抛物线形(子弹状)。在肺动脉高压中,血管顺应性的改变导致血液在收缩早期最大加速,肺动脉加速时间(AcT,或达到峰值速度的时间)缩短。在更严重的病例中,可见收缩中期切迹,这与血流快速减速有关,随后在收缩晚期速度短暂再次增加。我们对19例慢性阻塞性肺疾病成年患者进行了双功多普勒检查、剑突下途径检查和右心导管检查。在所有获得高质量多普勒记录的病例中,该研究都具有诊断价值。发现静息时AcT与肺动脉平均压或收缩压之间存在相关性。通过脉冲多普勒,即使在轻度高血压情况下,也能够对肺气肿患者的肺动脉压做出明显准确的预测。我们认为这种方法是对肺气肿患者进行无创检查的一种简单可靠的辅助手段,并且是经典胸骨旁途径的良好替代方法,而经典胸骨旁途径在这些患者中往往不可行。

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