González-Clemente J M, Pedrol E, Sanz B, Azón A, Miró J M, Mallolas J, Mensa J, Soriano E
Servicio de Enfermedades Infecciosas, Hospital Clínic i Provincial, Barcelona.
Rev Clin Esp. 1991 Apr;188(6):288-94.
We here present the clinical cases of two homosexual patients, carriers of human immunodeficiency virus (HIV), who later presented a syphilis infection and who after receiving the usually recommended treatment, suffered a relapse of the infection six months afterwards, with neurologic involvement in one case. The clinical characteristics are discussed as well as the diagnostic and therapeutic problems which syphilis infection presents in HIV infected patients. Serological results are comparable to those of the general population, although face positives have been occasionally reported as well as some abnormally elevated titers. It is possible that neurosyphilis might be more frequent and of earlier appearance in HIV infected patients. Therefore, it might be necessary to carry out a spinal fluid exam, in these type of patients, in order to rule out the existence of an early and/or asymptomatic neurologic affectation and give the appropriate antibiotic treatment.
我们在此呈现两名感染人类免疫缺陷病毒（HIV）的同性恋患者的临床病例，他们后来感染了梅毒，在接受通常推荐的治疗后，六个月后感染复发，其中一例出现神经系统受累。本文讨论了梅毒感染在HIV感染患者中呈现的临床特征以及诊断和治疗问题。血清学结果与普通人群相当，尽管偶尔也有假阳性报告以及一些异常升高的滴度。在HIV感染患者中，神经梅毒可能更常见且出现更早。因此，对于这类患者，可能有必要进行脑脊液检查，以排除早期和/或无症状神经系统病变的存在，并给予适当的抗生素治疗。
