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人类基因组计划:为生物学和医学创建基础设施。

The Human Genome Project: creating an infrastructure for biology and medicine.

作者信息

Yager T D, Nickerson D A, Hood L E

机构信息

NSF Science and Technology Center for Molecular Biotechnology, California Institute of Technology, Pasadena 91125.

出版信息

Trends Biochem Sci. 1991 Dec;16(12):454, 456, 458 passim. doi: 10.1016/0968-0004(91)90177-w.

Abstract

The Human Genome Project (HGP) is an international effort to map and sequence the human genome. It combines skills from diverse fields of biological and technological research, thus establishing deeper interactions between scientific disciplines. The combination of these skills should stimulate many advances in both pure and applied fields of research and give rise to new, interdisciplinary training programs. Some critics say that the HGP will damage biomedical research; however, we argue that it will bring new funds to the field and create a large ripple effect by providing new research opportunities through its discoveries.

摘要

人类基因组计划(HGP)是一项绘制人类基因组图谱并进行测序的国际合作项目。它融合了生物和技术研究不同领域的技能,从而在各科学学科之间建立了更深入的互动。这些技能的结合应能推动纯研究和应用研究领域取得诸多进展,并催生新的跨学科培训项目。一些批评者称人类基因组计划会损害生物医学研究;然而,我们认为它将为该领域带来新资金,并通过其发现提供新的研究机会,从而产生巨大的连锁反应。

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