Bergmann H, Blauhut B, Gassner W, Haider M
Ludwig-Boltzmann-Institut für Experimentelle Anästhesiologie und Intensivmedizinische Forschung, Linz.
Wien Med Wochenschr. 1991;141(21):485-92.
A new method of blood preparation by use of a multiple plastic bag system is prescribed. Buffy coat free red cell suspensions in additive solution (SAG-M), fresh frozen (recovered) plasma and random platelet concentrates can thus be produced. Apart from the so far clinically not instantaneously available stored platelets the storage time of the red cells is remarkably increased up to 42 to 49 days and the cellular contaminations (red cells and leucocytes in platelet concentrates, thrombocytes and leucocytes in FFP) are markedly diminished leading to a higher quality of these components. The Red Cross Blood Transfusion Service of Upper Austria presents its data obtained by the use of a quadruple plastic bag (RC Transfusion Production Center Eugendorf/Salzburg) with cellular contamination parameters far below the generally accepted limits. Apart from the increased quality of the components a very high level of clinical acceptance concerning especially the stored random platelet concentrates has been experienced. In conclusion the necessity of changing to a multiple bag system is strongly emphasized thus not only better fulfilling the clinical needs for the different blood components but also delivering higher qualities. Red cell preparations containing the buffy coat should therefore not be used any longer.
规定了一种使用多层塑料袋系统制备血液的新方法。由此可以制备添加剂溶液（SAG-M）中无白细胞层的红细胞悬液、新鲜冰冻（回收）血浆和随机血小板浓缩物。除了目前临床上不能即时获得的储存血小板外，红细胞的储存时间显著延长至42至49天，细胞污染（血小板浓缩物中的红细胞和白细胞、新鲜冰冻血浆中的血小板和白细胞）明显减少，从而提高了这些成分的质量。奥地利上奥地利州红十字会输血服务中心展示了其使用四重塑料袋（RC输血生产中心，欧根多夫/萨尔茨堡）获得的数据，其细胞污染参数远低于普遍接受的限度。除了成分质量提高外，尤其是储存的随机血小板浓缩物获得了非常高的临床接受度。总之，强烈强调改用多层袋系统的必要性，这样不仅能更好地满足临床对不同血液成分的需求，还能提供更高的质量。因此，不应再使用含有白细胞层的红细胞制剂。
