McGregor D H, Lee S H, McMahon M F
Laboratory Service, Department of Veterans Affairs Medical Center, Kansas City, MO 64128.
Ann Clin Lab Sci. 1991 Nov-Dec;21(6):413-9.
A case is reported of polypoid adenosquamous carcinosarcoma with blastomatous features arising in the epiglottis. A 69-year-old man with hoarseness and sore throat was found to have a six cm pedunculated mass located on the epiglottis. Upon examination by light microscopy, it was found that the tumor was composed of not only well to poorly differentiated in situ and invasive squamous cell carcinoma but also adenocarcinoma with blastomatous features and a malignant primitive stroma, with features of undifferentiated sarcoma and focal chondrosarcomatous differentiation. To the best of our knowledge, this appears to be the second case of laryngeal adenosquamous carcinosarcoma with blastomatous features reported in the English literature and the third case in the world literature.
报告了1例起源于会厌的具有母细胞瘤特征的息肉状腺鳞癌肉瘤病例。一名69岁男性，有声音嘶哑和咽痛症状，发现会厌有一个6厘米的带蒂肿物。光镜检查发现，肿瘤不仅由高分化至低分化的原位和浸润性鳞状细胞癌组成，还包括具有母细胞瘤特征的腺癌和恶性原始间质，具有未分化肉瘤特征和局灶性软骨肉瘤分化。据我们所知，这似乎是英文文献中报道的第二例具有母细胞瘤特征的喉腺鳞癌肉瘤病例，也是世界文献中的第三例。
