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长链二醇:一种来自嗜热细菌的新型膜脂。

Long-chain diols: a new class of membrane lipids from a thermophilic bacterium.

作者信息

Pond J L, Langworthy T A, Holzer G

出版信息

Science. 1986 Mar 7;231(4742):1134-6. doi: 10.1126/science.231.4742.1134.

DOI:10.1126/science.231.4742.1134
PMID:17818542
Abstract

Glycerol-derived membrane lipids are essentially absent in the thermophilic bacterium Thermomicrobium roseum. A series of straight chain and internally methyl-branched 1,2-diols of carbon numbers C(18) to C(23) were found to replace glycerolipids in this bacterium. Fatty acids were present but were ester-linked to the diols or amide-linked to polar heads groups and not to glycerol. This thermophile has evolved the integration of diols as a novel approach for the construction of its cytoplasmic membrane.

摘要

嗜热细菌玫瑰色嗜热栖菌中基本不存在甘油衍生的膜脂。已发现一系列碳数为C(18)至C(23)的直链和内部甲基支链的1,2 -二醇在该细菌中取代了甘油脂。脂肪酸存在,但它们与二醇酯键相连或与极性头部基团酰胺键相连,而不与甘油相连。这种嗜热菌已经进化出将二醇整合作为构建其细胞质膜的一种新方法。

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