Homma A, Niina R, Ishii T, Hasegawa K
Department of Psychiatry, Tokyo Metropolitan Institute of Gerontology, Japan.
Alzheimer Dis Assoc Disord. 1991;5 Suppl 1:S40-8. doi: 10.1097/00002093-199100051-00008.
GBS scale with four subscales and 26 total items is a behavior rating scale for dementia syndromes, and is now being used as one of the measures to assess the effects of drug therapy in dementia in Japan. In this article, the reliability and validity of the Japanese version of GBS Scale (GBSS-J) in 246 patients with dementia are examined. Two pairs of raters independently rated 20 patients to test inter-rater reliability of the 26 items. Pearson's correlation coefficients indicated good agreement between the raters except for nine items. The validity of the 26 items was examined by comparing them with the Functional Assessment Staging. Physical disability was evaluated by the Rapid Disability Rating Scale. Twenty items of GBSS-J measured the severity of dementia with sufficient validity. In addition, the items of eating, impaired physical activity, impaired wakefulness, and irritability were related to severity of physical disability rather than to dementia by the results from an analysis of variance and covariance. Although internal reliabilities by Cronbach's alpha of the three subscales were relatively high except for the subscale of different symptoms common in dementia, a factor analysis of the 26 items raised questions concerning the construct validity of the original four subscales.
具有四个分量表和共26个条目的GBS量表是一种用于痴呆综合征的行为评定量表，目前在日本被用作评估痴呆药物治疗效果的指标之一。在本文中，对246例痴呆患者的日本版GBS量表（GBSS-J）的信度和效度进行了检验。两组评定者独立对20例患者进行评分，以检验26个条目的评定者间信度。除9个条目外，Pearson相关系数表明评定者之间具有良好的一致性。通过与功能评估分期进行比较，检验了26个条目的效度。采用快速残疾评定量表评估身体残疾情况。GBSS-J的20个条目在测量痴呆严重程度方面具有足够的效度。此外，通过方差分析和协方差分析结果显示，进食、身体活动受损、觉醒障碍和易激惹等条目与身体残疾严重程度相关，而非与痴呆相关。尽管除痴呆常见不同症状分量表外，其他三个分量表的Cronbach's α内部信度相对较高，但对26个条目的因子分析对原始四个分量表的结构效度提出了疑问。
