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[Y染色体异染色质与人类形态生理变异性]

[Y chromosome heterochromatin and human morphophysiological variability].

作者信息

Nazareko S A, Puzyrev V P, Lemza S V

机构信息

Cytogenetics Laboratory, Tomsk Scientific Center, USSR Academy of Medical Sciences.

出版信息

Yi Chuan Xue Bao. 1991;18(5):424-30.

PMID:1782001
Abstract

Eighty morphophysiological traits were studied in 55 males with a morphologically identical heterochromatin subtotal deletion of Y chromosome and in 55 males with a normal Y chromosome. No significant differences were found between these groups in mean values of most traits except some hematologic parameters. Using the pattern recognition algorithm a combination of 20 traits which differentiated the groups under comparison with the recognition errors 4.6% was extracted. The recognition system consisted the informative traits including electrocardiographic parameters (25% of the traits), some anthropological and hematologic traits and subjects' age. The results suggest that the Y chromosome heterochromatin appears to have a modifying effect on the phenotypic relationship between morphophysiological traits during human ontogenesis.

摘要

对55名Y染色体形态相同的异染色质部分缺失男性和55名Y染色体正常男性的80个形态生理特征进行了研究。除了一些血液学参数外,这些组在大多数特征的平均值上没有发现显著差异。使用模式识别算法,提取了20个特征的组合,该组合在区分比较组时识别错误率为4.6%。识别系统由信息特征组成,包括心电图参数(占特征的25%)、一些人类学和血液学特征以及受试者的年龄。结果表明,Y染色体异染色质在人类个体发育过程中似乎对形态生理特征之间的表型关系具有修饰作用。

相似文献

1
[Y chromosome heterochromatin and human morphophysiological variability].[Y染色体异染色质与人类形态生理变异性]
Yi Chuan Xue Bao. 1991;18(5):424-30.
2
[Heterochromatin of the Y-chromosome and variability of human morphophysiological traits].
Genetika. 1989 Jul;25(7):1286-93.
3
[Reciprocal variability of Q-heterochromatin level in the human genome].
Biull Eksp Biol Med. 1986 Jun;101(6):736-8.
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Genetika. 1984 Mar;20(3):496-500.
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[Intra-individual polymorphism of human Y chromosome as a result of deletion in the heterochromatin region].[人类Y染色体因异染色质区域缺失导致的个体内多态性]
Genetika. 1987 May;23(5):918-21.
6
[High frequency of subtotal deletion of the Y-chromosome hetero-chromatin in Khanty from the lower Ob River area].
Genetika. 1984 Sep;20(9):1549-53.
7
The use of in situ hybridization for detection of loss of the Y chromosome in males with pancytopenia.应用原位杂交技术检测全血细胞减少男性患者的Y染色体缺失。
Hematol Pathol. 1989;3(4):177-83.
8
Heterochromatin is not an adequate explanation for close proximity of interphase chromosomes 1--Y, 9--Y, and 16--Y in human spermatozoa.异染色质并不能充分解释人类精子中1号染色体与Y染色体、9号染色体与Y染色体以及16号染色体与Y染色体在间期的紧密靠近现象。
Exp Cell Res. 2001 May 1;265(2):283-7. doi: 10.1006/excr.2001.5193.
9
[Variability of the heterochromatic regions of human chromosomes 1, 9, 16, and Y].[人类1号、9号、16号和Y染色体异染色质区域的变异性]
Genetika. 1980 Apr;16(4):720-6.
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[Polymorphism of the heterochromatic regions of chromosomes 1, 9, 16 and Y and mental retardation].[1、9、16号染色体及Y染色体异染色质区多态性与智力发育迟缓]
Genetika. 1984 Jan;20(1):177-82.