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[人类1号、9号、16号染色体以及Y染色体的异染色质区域与表型]

[Heterochromatic regions of human chromosomes 1, 9, 16 and Y and the phenotype].

作者信息

Podgol'nikova O A, Grigor'eva N M, Bliumina M G

出版信息

Genetika. 1984 Mar;20(3):496-500.

PMID:6232170
Abstract

The relationship between variability of the heterochromatic regions of chromosomes 1, 9, 16, Y and the anthropometric characteristics (the height, the biacromial diameter and weight) was studied in two groups of children; 70 children had embryopathies of unknown etiology and 40 children had the Down syndrome. The positive statistically significant correlation of the C-segments lengths of chromosomes 1, 9, 16, their sum included, and above characteristics was found. The correlation coefficients of Y-chromosome were non-significant. The problems of functional role of the structural heterochromatin and its influence on viability and physical development of the organism are discussed.

摘要

对两组儿童研究了1号、9号、16号染色体及Y染色体异染色质区域的变异性与人体测量特征(身高、肩峰间径和体重)之间的关系;70名儿童患有病因不明的胚胎病,40名儿童患有唐氏综合征。发现1号、9号、16号染色体C段长度及其总和与上述特征呈统计学显著正相关。Y染色体的相关系数无统计学意义。讨论了结构异染色质的功能作用及其对机体生存能力和身体发育的影响问题。

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