Institute of Medical Physics, School of Physics, University of Sydney, Department of Radiation Oncology, Royal Prince Alfred Hospital, Sydney, Australia.
Med Phys. 2007 Jul;34(7):3045-53. doi: 10.1118/1.2748103.
Kilovoltage x-ray beams are used to treat cancer on or close to the skin surface. Many clinical cases use high atomic number materials as shielding to reduce dose to underlying healthy tissues. In this work, we have investigated the effect on both the surface dose and depth doses in a water phantom with lead shielding at depth in the phantom. The EGSnrc Monte Carlo code was used to simulate the water phantom and to calculate the surface doses and depth doses using primary x-ray beam spectra derived from an analytical model. The x-ray beams were in the energy range of 75-135 kVp with field sizes of 2, 5 and 8 cm diameter. The lead sheet was located beneath the water surface at depths ranging from 0.5-7.5 cm. The surface dose decreased as the lead was positioned closer to the water surface and as the field size was increased. The variation in surface dose as a function of x-ray beam energy was only small but the maximum reduction occurred for the 100 kVp x-ray beam. For the 8 cm diameter field with the lead at 1 cm depth and using the 100 kVp x-ray beam, the surface dose was reduced to 0.898 of the surface dose in the water phantom only. Measured surface dose changes, using a Farmer-type ionization chamber, agreed with the Monte Carlo calculated doses. Calculated depth doses in water with a lead sheet positioned below the surface showed that the dose fall-off increased as the lead was positioned closer to the water surface as compared to the depth dose in the water phantom only. Monte Carlo calculations of the total x-ray beam spectrum at the water surface showed that the total fluence decreased due to a reduction in backscatter from within the water and very little backscatter from the lead. The mean energy of the x-ray spectrum varied less than 1 keV, with the lead at 1 cm beneath the water phantom surface. As the Monte Carlo calculations showed good agreement with the measured results, this method can be used to verify surface dose changes in clinical situations where measurements are difficult. The clinical impact of the use of lead must be considered in the dose prescription for patients being treated with kilovoltage x-ray beams.
千伏 X 射线束用于治疗皮肤表面或附近的癌症。许多临床病例使用高原子序数材料作为屏蔽物,以减少对下面健康组织的剂量。在这项工作中,我们研究了在水模体中使用铅屏蔽物时,屏蔽物深度处的表面剂量和深度剂量的影响。使用 EGSnrc 蒙特卡罗代码模拟水模体,并使用从解析模型导出的初级 X 射线束谱计算表面剂量和深度剂量。X 射线束的能量范围为 75-135 kVp,射野尺寸为 2、5 和 8 cm 直径。铅片位于水面以下 0.5-7.5 cm 深处。随着铅片更接近水面和射野尺寸的增加,表面剂量降低。随着 X 射线束能量的变化,表面剂量的变化很小,但在 100 kVp X 射线束时最大减少。对于 8 cm 直径的射野和位于 1 cm 深处的铅片,并使用 100 kVp X 射线束,表面剂量仅降低到水模体中表面剂量的 0.898。使用 Farmer 型电离室测量的表面剂量变化与蒙特卡罗计算的剂量相符。在水模体中放置在水面以下的铅片的水中深度剂量显示,与仅在水模体中的深度剂量相比,随着铅片更接近水面,剂量下降增加。在水面处的总 X 射线束谱的蒙特卡罗计算表明,由于水中的反向散射减少和来自铅的反向散射很少,总注量减少。由于铅片位于水模体表面以下 1 cm 处,X 射线谱的平均能量变化小于 1 keV。由于蒙特卡罗计算与测量结果吻合良好,因此该方法可用于验证临床情况下难以进行测量的表面剂量变化。在使用千伏 X 射线束治疗患者时,必须考虑铅的使用对剂量规定的临床影响。