Tanaka Kaori, Nakao Ken'ichi, Mikamo Hiroshige, Watanabe Kunitomo
Division of Anaerobe Research, Life Science Research Center, Gifu University.
Rinsho Biseibutshu Jinsoku Shindan Kenkyukai Shi. 2006;17(2):115-24.
Commonly isolated anaerobic gram-negative rods (4 genus 64 strains), some other important gram-negative anaerobic species (9 genus 45 strains), and cigar-shaped clostridia (11 strains) were studied on their susceptibility patterns to 6 agents on "Microring AN". Some modifications were made in the methods and interpretation of results. Susceptibility patterns to erythromycin, rifampicin, colistin, benzylpenicillin, kanamycin, and vancomycin were following (sensitive [S], intermediate [I], resistant [R], variable [V]): for Bacteroides fragilis group, V, S, R, R, R, R, respectively; for non-pigmented Prevotella, V, S, V, V, R, R, respectively; for pigmented Prevotella, S, S, SR, V, V, R, respectively: for Fusobacterium nucleatum/necrophorum, R(S), S(I), S(IR), S(R), S, R, respectively; and for F. varium, R, R, S/I, R(S), S, R, respectively. Some results were different from that in the data table in the instruction of "Microring AN", because of differences of methodology and changes of susceptibility of those species during years. As to the other groups, that are not included in the data table in the instruction, results were following: for Bilophila wadsworthia, R, R, S, R, S, R, respectively; Desulfovibrio, V, R(S), R, R, S, R, respectively; for cigar-shaped clostridia, V, S(R), R, R, S(R), S, respectively. "Microring AN" was useful for presumptive identification in genus, species, or group level, though morphological observation and some additional simple tests such as bile-sensitivity and catalase were essential.
对常见的厌氧革兰氏阴性杆菌（4属64株）、其他一些重要的革兰氏阴性厌氧菌种（9属45株）以及雪茄形梭菌（11株）进行了研究，观察它们在“Microring AN”上对6种药物的敏感性模式。在方法和结果解读方面做了一些修改。它们对红霉素、利福平、黏菌素、苄青霉素、卡那霉素和万古霉素的敏感性模式如下（敏感[S]、中介[I]、耐药[R]、可变[V]）：脆弱拟杆菌群分别为V、S、R、R、R、R；非色素普雷沃菌分别为V、S、V、V、R、R；色素普雷沃菌分别为S、S、SR、V、V、R；具核/坏死梭杆菌分别为R(S)、S(I)、S(IR)、S(R)、S、R；多变梭杆菌分别为R、R、S/I、R(S)、S、R。由于方法学差异以及这些菌种多年来敏感性的变化，一些结果与“Microring AN”说明书数据表中的结果不同。对于说明书数据表中未包含的其他菌群，结果如下：沃兹沃思嗜胆菌分别为R、R、S、R、S、R；脱硫弧菌分别为V、R(S)、R、R、S、R；雪茄形梭菌分别为V、S(R)、R、R、S(R)、S。“Microring AN”对于属、种或菌群水平的初步鉴定很有用，不过形态学观察以及一些额外的简单试验如胆汁敏感性试验和过氧化氢酶试验必不可少。
