Pujary K, Rangarajan S, Nayak D R, Balakrishnan R, Ramakrishnan V
Department of ENT - Head & Neck Surgery, Kasturba Medical College & Hospital, Manipal, India.
Int J Oral Maxillofac Surg. 2008 Jan;37(1):93-6. doi: 10.1016/j.ijom.2007.06.014. Epub 2007 Sep 5.
Hyalinizing clear cell carcinoma is a rare, low-grade neoplasm of the minor salivary glands. It is composed exclusively of epithelial cells with optically clear cytoplasm. There are only a few isolated cases reported in the literature involving the base of tongue. The treatment of choice is wide excision and selective neck dissection, with or without radiotherapy. The prognosis of these tumours is good. A 57-year-old male patient presented with a lesion in the base of tongue, which was well enhanced on contrast computerized tomography scan. Once confirmed by biopsy, the hyalinizing clear cell carcinoma was resected via a transcervical approach. The patient underwent postoperative radiotherapy. There was no evidence of locoregional recurrence or distant metastasis at 18 months of follow up.
透明细胞癌是一种罕见的小涎腺低度肿瘤。它仅由具有光学透明细胞质的上皮细胞组成。文献中仅有少数孤立病例报道涉及舌根。首选的治疗方法是广泛切除和选择性颈清扫术，可联合或不联合放疗。这些肿瘤的预后良好。一名57岁男性患者出现舌根病变，在对比增强计算机断层扫描上有良好强化。经活检确诊后，通过经颈入路切除透明细胞癌。患者接受了术后放疗。随访18个月时，没有局部区域复发或远处转移的证据。
