Green Alexander L, Pereira Erlick A C, Kelly Dominic, Richards Peter G, Pike Michael G
Department of Neurosurgery, The Radcliffe Infirmary, Woodstock Road, Oxford, OX2 6HE, United Kingdom.
J Clin Neurosci. 2007 Nov;14(11):1049-54. doi: 10.1016/j.jocn.2006.11.004. Epub 2007 Sep 5.
All 253 children receiving neurosurgical intervention for hydrocephalus (HCP) at a single British Neurosurgical Unit over a decade were investigated by retrospective case note review. Referral rates and mean age at presentation remained stable throughout, as did proportions of children presenting due to myelomeningocoele or meningitis. Comparing the first and second halves of the decade, the predominant aetiologies (intraventricular haemorrhage [IVH] at <1 year and brain tumour at 1-16 years) reduced from comprising half (70/129) of all cases to just over one-third (43/124). Other significant changes included a 45% reduction in neonatal IVH and a 179% increase in rare miscellaneous disorders. Outcome after 4 years of follow-up for all patients showed 44.4% without deficit, 11.9% with non-cognitive neurological deficits only, 11.5% with cognitive impairment only, 13.5% with both cognitive and neurological impairments, and 15.5% mortality.
在十年间，一家英国神经外科单位对所有253名接受脑积水（HCP）神经外科手术干预的儿童进行了回顾性病例记录审查。转诊率和就诊时的平均年龄在整个十年间保持稳定，因脊髓脊膜膨出或脑膜炎就诊的儿童比例也是如此。比较十年的前半期和后半期，主要病因（1岁以下儿童的脑室内出血[IVH]和1 - 16岁儿童的脑肿瘤）在所有病例中所占比例从一半（70/129）降至略超过三分之一（43/124）。其他显著变化包括新生儿IVH减少45%，罕见杂症增加179%。对所有患者进行4年随访后的结果显示，44.4%无缺陷，11.9%仅有无认知神经缺陷，11.5%仅有认知障碍，13.5%既有认知障碍又有神经障碍，15.5%死亡。
