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结直肠癌随访中癌胚抗原(CEA)检测:患者怎么看?

Carcinoembryonic antigen (CEA) testing in colorectal cancer follow up: what do patients think?

作者信息

Steele Nicola, Haigh Rachel, Knowles Gillian, Mackean Melanie

机构信息

The Beatson West of Scotland Cancer Centre, Glasgow, UK.

出版信息

Postgrad Med J. 2007 Sep;83(983):612-4. doi: 10.1136/pgmj.2007.059634.

Abstract

The carcinoembryonic antigen (CEA) blood test is included in most colorectal cancer follow up protocols, despite little clear evidence for its cost-effectiveness and survival benefit. In this study, patients' views were sought on the use of the CEA blood test in their follow up. Strong associations were found between the age of a patient's children and their concern about cancer recurrence and between concern about recurrence and anxiety about CEA test results (p<0.0001). Many patients expressed a desire for prognostic information, however uncertain or poor. Patients' views should be sought when designing colorectal cancer follow up protocols to ensure their needs are adequately addressed.

摘要

癌胚抗原(CEA)血液检测包含在大多数结直肠癌随访方案中,尽管几乎没有明确证据表明其具有成本效益和生存获益。在本研究中,我们征求了患者对随访中使用CEA血液检测的看法。发现患者子女的年龄与他们对癌症复发的担忧之间,以及对复发的担忧与对CEA检测结果的焦虑之间存在强烈关联(p<0.0001)。许多患者表达了对预后信息的渴望,无论这种信息多么不确定或不准确。在设计结直肠癌随访方案时,应征求患者的意见,以确保他们的需求得到充分满足。

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