Schripsema Jan, Caprini Geisa Paulino, van der Heijden Rob, Bino Raoul, de Vos Ric, Dagnino Denise
Analytical Biotechnology, Department of Biotechnology, Delft University of Technology, Julianalaan, Delft, The Netherlands.
J Nat Prod. 2007 Sep;70(9):1495-8. doi: 10.1021/np070116+. Epub 2007 Sep 8.
From the aerial parts of Pentas lanceolata, belonging to the family Rubiaceae, a series of iridoid glucosides was isolated by preparative HPLC. Seven iridoid glucosides were identified. Besides asperuloside and asperulosidic acid, characteristic iridoids for Rubiaceae, five new iridoids were isolated, namely, tudoside (1), 13R-epi-gaertneroside (2), 13R-epi-epoxygaertneroside (3), and a mixture of E-uenfoside (4) and Z-uenfoside (5). Further, it was shown that the compound reported as citrifolinin B (6) is in fact the same as tudoside and should be revised. Also, the configuration of the previously reported iridoids gaertneroside and epoxygaertneroside has been elucidated.
从茜草科五星花的地上部分，通过制备型高效液相色谱法分离得到了一系列环烯醚萜苷。鉴定出了七种环烯醚萜苷。除了茜草苷和茜草酸（茜草科的特征性环烯醚萜）外，还分离出了五种新的环烯醚萜，即土多苷（1）、13R-表-盖尔特苷（2）、13R-表-环氧盖尔特苷（3）以及E-乌恩福苷（4）和Z-乌恩福苷（5）的混合物。此外，已证明报道为柠檬叶苷B（6）的化合物实际上与土多苷相同，应予以修正。同时，也阐明了先前报道的环烯醚萜盖尔特苷和环氧盖尔特苷的构型。
