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一种综合药物管理的创新方法。

An innovative approach to integrated medicines management.

作者信息

Scullin Claire, Scott Michael G, Hogg Anita, McElnay James C

机构信息

Clinical and Practice Research Group, School of Pharmacy, Queen's University Belfast, Belfast, UK.

出版信息

J Eval Clin Pract. 2007 Oct;13(5):781-8. doi: 10.1111/j.1365-2753.2006.00753.x.

Abstract

RATIONALE, AIMS AND OBJECTIVES: To determine whether an increased input by clinical pharmacists at each stage of the patient's hospital journey, from admission through discharge, resulted in an enhanced level of patient care as measured by a number of clinical and economic outcomes.

METHODS

This project was designed to address medicines management issues in patients deemed at risk of drug-related problems. During the project, these latter patients at the time of admission were randomly assigned to an integrated medicines management (IMM) service group (n = 371) or regular hospital care group (n = 391). The IMM service involved comprehensive pharmaceutical care provided by a pharmacy team throughout each of three stages: patient admission, inpatient monitoring and counselling, and patient discharge.

RESULTS

Patients who received the IMM service benefited from a reduced length of hospital stay [by 2 days (P = 0.003; independent samples t-test log(e))]. IMM patients also had a decreased rate of readmission over a 12-month follow-up period (40.8% vs. 49.3%; p = 0.027; Fisher's exact test) and an increased time to readmission [20 days longer (P = 0.0356; log rank test)]. A numbers-needed-to-treat calculation indicated that for approximately every 12 patients receiving the IMM service, one readmission to hospital, within 12 months of discharge, would be prevented. The new service was welcomed by cognate health care professionals.

CONCLUSION

The IMM service proved very effective and can be used as a template to support the implementation of comprehensive pharmaceutical care as a routine service across Northern Ireland and beyond.

摘要

原理、目的与目标:确定临床药师在患者住院期间从入院到出院的每个阶段增加介入,是否会通过一系列临床和经济结果衡量,提升患者护理水平。

方法

本项目旨在解决被认为有药物相关问题风险患者的用药管理问题。在项目期间,这些患者在入院时被随机分配到综合用药管理(IMM)服务组(n = 371)或常规医院护理组(n = 391)。IMM服务包括药房团队在三个阶段提供的全面药学服务:患者入院、住院监测与咨询以及患者出院。

结果

接受IMM服务的患者住院时间缩短[缩短2天(P = 0.003;独立样本t检验对数(e))]。IMM患者在12个月随访期内的再入院率也有所降低(40.8%对49.3%;p = 0.027;Fisher精确检验),再入院时间增加[长20天(P = 0.0356;对数秩检验)]。需治疗人数计算表明,大约每12名接受IMM服务的患者中,就有1名在出院后12个月内可避免再次入院。该新服务受到相关医疗保健专业人员的欢迎。

结论

IMM服务证明非常有效,可作为模板支持在北爱尔兰及其他地区将全面药学服务作为常规服务实施。

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