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测量药学护理包的提供对患者结局的影响:一项观察性研究。

Measuring the impact of pharmaceutical care bundle delivery on patient outcomes: an observational study.

机构信息

Pharmacy Department, The Prince Charles Hospital, Rode Rd, Chermside, Qld, 4032, Australia.

Metro North Clinical Governance, Metro North Health, Herston, Australia.

出版信息

Int J Clin Pharm. 2024 Oct;46(5):1172-1180. doi: 10.1007/s11096-024-01750-w. Epub 2024 May 28.

Abstract

BACKGROUND

Clinical pharmacists perform activities to optimise medicines use and prevent patient harm. Historically, clinical pharmacy quality indicators have measured individual activities not linked to patient outcomes.

AIM

To determine the proportion of patients who receive a pharmaceutical care bundle (PCB) (consisting of a medication history, medication review, discharge medication list and medicines information on the discharge summary) as well as investigate the relationship between delivery of this PCB and patient outcomes.

METHOD

Pharmaceutical care bundle activities were defined within state-wide (Queensland, Australia) clinical information systems and datasets were linked. An observational study using routinely recorded data was performed at ten participating sites for adult patients who had a non-same day hospital stay. The association between extent of PCB delivery and three patient outcomes were investigated: length of stay (LOS), unplanned readmission, and mortality.

RESULTS

In total 283,813 patient hospital stays were evaluated. The delivery of the PCB occurred in 26.9% of patients at the ten participating hospital sites, ranging from 0.6 to 61.2% across sites. Patients with a longer LOS were more likely to receive delivery of the complete PCB (P < 0.001). There was no correlation between PCB and hospital standardised mortality ratio (r = 0.03, p = 0.93). Higher rates of delivery of the PCB were associated with lower rates of unplanned readmission within 30 days (r = - 0.993, p < 0.001).

CONCLUSION

A complete PCB was delivered to 26.9% of patients and was associated with a significantly lower rate of unplanned readmission within 30 days.

摘要

背景

临床药师开展各种活动以优化药物使用,防止患者受到伤害。历史上,临床药学质量指标衡量的是与患者结局无关的单项活动。

目的

确定接受药物治疗管理包(包含用药史、药物审查、出院带药清单和出院小结中的用药信息)的患者比例,并调查提供该药物治疗管理包与患者结局之间的关系。

方法

在全州(澳大利亚昆士兰州)临床信息系统中定义药物治疗管理包活动,并对十个参与地点的非当日出院成年患者进行常规记录数据的观察性研究。调查药物治疗管理包的提供程度与三个患者结局之间的关联:住院时间(LOS)、非计划再入院和死亡率。

结果

共评估了 283813 例患者的住院情况。在十个参与医院地点中,26.9%的患者接受了药物治疗管理包,各医院地点的提供率在 0.6%至 61.2%之间。住院时间较长的患者更有可能接受完整的药物治疗管理包(P<0.001)。药物治疗管理包与医院标准化死亡率比(r=0.03,p=0.93)之间没有相关性。药物治疗管理包提供率较高与 30 天内非计划再入院率较低相关(r=−0.993,p<0.001)。

结论

26.9%的患者接受了完整的药物治疗管理包,与 30 天内非计划再入院率显著降低相关。

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