Mahmood Saad Bin Zafar, Rehman Fazal, Jamal Aisha, Meghani Naureen Ali, Iqbal Madiha, Amirali Ambreen, Almas Aysha
The Aga Khan University, Karachi, Pakistan.
Dow University of Health Sciences, Karachi, Pakistan.
Hosp Pharm. 2024 Dec;59(6):624-630. doi: 10.1177/00185787241253442. Epub 2024 May 28.
Medication reconciliation is one of the best measures to prevent medication-related errors at the time of admission and discharge of patients. We conducted a quasi-experimental study to evaluate the impact of a Medication reconciliation improvement package (intervention) on adherence to medication reconciliation at the time of admission in Department of Internal Medicine. The study included all adult patients admitted to internal medicine from August 2019 to December 2020. Pre-intervention data on adherence to medication reconciliation was less than 50%. The study involved creation of a quality improvement team to conduct a root-cause analysis which identified the need to target physician related issues and hence drafted a medication reconciliation improvement package which included meetings with physicians on the internal medicine floor, dedicated WhatsApp groups for repeated reminders, and appreciation messages for timely adherence. We used the Chi Square test to check the association between adherence to medication reconciliation and physicians and acuity level. We included 7914 records of patients, in which 4471 participants (56.4%) were from pre-intervention phase and 3443 (43.5%) were from intervention groups. The overall adherence to medication reconciliation was 54.3% (4297/7914). Adherence of medication reconciliation increased from 44.4% (1983/4471) in the pre-intervention phase to 67.2% (2314/3443) in the intervention phase ( < .001). Improvement was observed in adherence of medication reconciliation done by residents and in low acuity areas ( < .005). The Medical reconciliation improvement package is a simple low-cost intervention that resulted in improvement in adherence to medication reconciliation but needs further studies to assess its sustainability. However, it awaits to be seen if the same improvement can also be replicated to qualitative medication errors and clinical outcomes respectively.
用药核对是预防患者入院和出院时与用药相关错误的最佳措施之一。我们进行了一项准实验研究,以评估用药核对改进方案(干预措施)对内科入院时用药核对依从性的影响。该研究纳入了2019年8月至2020年12月期间内科收治的所有成年患者。干预前用药核对依从性的数据低于50%。该研究涉及组建一个质量改进团队进行根本原因分析,分析确定需要解决与医生相关的问题,因此起草了一份用药核对改进方案,其中包括在内科病房与医生开会、通过专门的WhatsApp群组反复提醒,以及对及时依从的表扬信息。我们使用卡方检验来检查用药核对依从性与医生及病情严重程度之间的关联。我们纳入了7914例患者记录,其中4471名参与者(56.4%)来自干预前阶段,3443名(43.5%)来自干预组。用药核对的总体依从率为54.3%(4297/7914)。用药核对的依从性从干预前阶段的44.4%(1983/4471)提高到干预阶段的67.2%(2314/3443)(P<0.001)。住院医师进行的用药核对以及低病情严重程度区域的用药核对依从性均有改善(P<0.005)。用药核对改进方案是一种简单的低成本干预措施,可提高用药核对的依从性,但需要进一步研究以评估其可持续性。然而,同样的改进是否也能分别复制到定性用药错误和临床结局上,还有待观察。