Benton Richard
Laboratory of Neurogenetics and Behavior, The Rockefeller University, 1230 York Avenue Box 63, New York, NY 10065, USA.
Trends Neurosci. 2007 Oct;30(10):512-9. doi: 10.1016/j.tins.2007.07.004. Epub 2007 Sep 6.
How the brain perceives volatile chemicals in the environment to evoke the appropriate behaviour is a fundamental question in sensory neuroscience. The olfactory system of the fruit fly, Drosophila melanogaster, has emerged as a powerful model system to address this problem. Recent analysis of the molecular, neuroanatomical and physiological properties of the olfactory circuits that detect the sex and social aggregation pheromone cis-vaccenyl acetate now provides one of the most comprehensive outlines for the neural basis of odour perception. This review describes these latest advances, discusses what they reveal about where stimulus sensitivity and specificity is encoded in olfactory circuits, and considers future questions.
大脑如何感知环境中的挥发性化学物质以引发适当行为是感觉神经科学中的一个基本问题。果蝇（Drosophila melanogaster）的嗅觉系统已成为解决这一问题的强大模型系统。最近对检测性和社会聚集信息素顺式-乙酸vaccenyl酯的嗅觉回路的分子、神经解剖学和生理学特性的分析，为气味感知的神经基础提供了最全面的概述之一。本综述描述了这些最新进展，讨论了它们揭示的嗅觉回路中刺激敏感性和特异性编码的位置，并考虑了未来的问题。
