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产前艾滋病毒监测数据在资源有限环境中评估预防母婴艾滋病毒传播项目的效用。

Utility of antenatal HIV surveillance data to evaluate prevention of mother-to-child HIV transmission programs in resource-limited settings.

作者信息

Bolu Omotayo, Anand Abhijeet, Swartzendruber Andrea, Hladik Wolfgang, Marum Lawrence H, Sheikh Abdullahi Ahmed, Woldu Aseged, Ismail Shabbir, Mahomva Agnes, Greby Stacie, Sabin Keith

机构信息

Centers for Disease Control and Prevention/National Center for HIV, Hepatitis, STD, and TB Prevention/Global AIDS Program, Atlanta, GA, USA.

出版信息

Am J Obstet Gynecol. 2007 Sep;197(3 Suppl):S17-25. doi: 10.1016/j.ajog.2007.03.082.

Abstract

Prevention of mother-to-child human immunodeficiency virus (HIV) transmission (PMTCT) programs are expanding in resource-limited countries and are increasingly implemented in antenatal clinics (ANC) in which HIV sentinel surveillance is conducted. ANC sentinel surveillance data can be used to evaluate the first visit of a pregnant woman to PMTCT programs. We analyzed data from Kenya and Ethiopia, where information on PMTCT test acceptance was collected on the 2005 ANC sentinel surveillance forms. For Zimbabwe, we compared the 2005 ANC sentinel surveillance data to the PMTCT program data. ANC surveillance data allowed us to calculate the number of HIV-positive women not participating in the PMTCT program. The percentage of HIV-positive women missed by the PMTCT program was 17% in Kenya, 57% Ethiopia, and 59% Zimbabwe. The HIV prevalence among women participating in PMTCT differed from women who did not. ANC sentinel surveillance can be used to evaluate and improve the first encounter in PMTCT programs. Countries should collect PMTCT-related program data through ANC surveillance to strengthen the PMTCT program.

摘要

预防母婴传播人类免疫缺陷病毒(HIV)(PMTCT)项目正在资源有限的国家不断扩展,并且越来越多地在开展HIV哨点监测的产前诊所(ANC)中实施。ANC哨点监测数据可用于评估孕妇首次就诊于PMTCT项目的情况。我们分析了来自肯尼亚和埃塞俄比亚的数据,这些数据是在2005年ANC哨点监测表格上收集的关于PMTCT检测接受情况的信息。对于津巴布韦,我们将2005年ANC哨点监测数据与PMTCT项目数据进行了比较。ANC监测数据使我们能够计算出未参与PMTCT项目的HIV阳性女性人数。在肯尼亚,PMTCT项目遗漏的HIV阳性女性比例为17%,在埃塞俄比亚为57%,在津巴布韦为59%。参与PMTCT的女性中的HIV流行率与未参与的女性不同。ANC哨点监测可用于评估和改善PMTCT项目中的首次接触情况。各国应通过ANC监测收集与PMTCT相关的项目数据,以加强PMTCT项目。

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